增强Cube FLAIR与增强T1WI序列在颅脑疾病中的对比研究

目的探讨增强Cube FLAIR序列在颅脑疾病中的应用价值,并与常规增强T1WI序列对比,是否可代替或作为补充扫描序列。材料与方法本研究纳入颅脑疾病患者25例作为研究对象,包括颅内单发肿瘤20例、脑炎2例、脑内多发转移瘤3例。25例颅脑疾病患者在GE 3.0 T上完成常规平扫各序列以及增强T1WI序列和矢状位增强Cube FLAIR序列的扫描。增强Cube FALIR序列扫描后在ADW 4.4工作站上进行横断面及冠状面的重建。结果增强Cube FLAIR与增强T1WI两序列上病变与白质及病变与脑脊液的信号强度比较差异有统计学意义(P0.05)。在增强Cube FLAIR与平扫T2 FLAIR两序列上病变与白质及病变与灰质的信号强度比较差异有显著统计学意义(P0.01)。在脑内单发肿瘤中有1例患者由于一侧面肌无力来诊,经检查发现右侧桥小脑角区占位,在增强Cube FLAIR序列上可以清楚地显示右侧面神经的增粗,而在其他序列上显示不清。2例脑炎患者在增强Cube FLAIR序列上较平扫T2 FLAIR序列及增强T1WI序列显示病变更清晰、范围更大。3例脑内多发转移瘤患者在增强Cube FLAIR序列上较增强T1WI序列显示的病灶数量更多,其中2例还可以看到脑膜的广泛转移。结论增强Cube FLAIR序列在颅脑疾病诊断方面有着重要的应用价值,可以作为中枢神经系统疾病磁共振扫描中的有益补充。

Comparative study on contrast-enhanced Cube FLAIR and T1WI sequences in craniocerebral diseases

Objective: To evaluate the diagnostic value of applying MR contrast-enhanced T1 weighted imaging and T2WI FLAIR CUBE sequence to diagnosis of craniocerebral diseases. Materials and Methods: Twenty-five subjects were included in this study. The patients were composed of 20 cases of single brain tumor, 2 cases of meningitis, and 3 cases of metastatic encephaloma. Twenty-five patients underwent T2 FLAIR, enhanced T1WI and enhanced sagittal Cube FLAIR imaging with the 3.0 T MR scanner. Multi-planar reconstruction and axial reconstruction were completed after enhanced Cube FLAIR scan in order to compare with enhanced T1WI sequence. Results: The signal ratios of lesion had significant difference in enhanced T1WI and enhanced Cube FLAIR (P<0.05), as well as enhanced Cube FLAIR and unenhanced T2 FLAIR (P<0.01). One patient diagnosed with cerebellopontine angle tumor presented with a 6-month history of a facial palsy. We could see clearly about the incrassate facial nerve, which is invisible on the other sequences. Compared with T2 FLAIR and enhanced T1WI, enhanced Cube FLAIR clearly demonstrated the scope of lesions. The enhanced Cube FLAIR sequence clearly depicted the distribution of metastatic lesions and the meningeal spread in the metastatic encephaloma patients as well as a much wider range compared with conventional enhanced T1WI. Conclusion: Enhanced Cube FLAIR sequence can be used as a conventional sequence in the diagnosis of central nervous diseases.