首页 | 本学科首页   官方微博 | 高级检索  
     

鸦胆子油乳联合放疗治疗骨转移癌疼痛的临床观察
引用本文:李兆元,余海英,宁四清,易铁男. 鸦胆子油乳联合放疗治疗骨转移癌疼痛的临床观察[J]. 中国疼痛医学杂志, 2012, 18(1): 35-37
作者姓名:李兆元  余海英  宁四清  易铁男
作者单位:湖北省襄阳市中心医院肿瘤科,襄阳,441021
摘    要:目的:评价鸦胆子油乳注射液联合放疗治疗骨转移癌疼痛的疗效及毒副作用。方法:66例骨转移癌疼痛的患者随机分为观察组(n=34)与对照组(n=32),两组均采用局部放疗DT=30GY/10F,观察组同时采用鸦胆子油乳30 ml静脉滴注,每天1次,21天为1疗程,分别以疼痛症状、X线平片等评价治疗的主观疗效和客观疗效,观察生存质量Karnofsky评分(KPS评分)变化,1年生存率及白细胞计数变化等指标。结果:鸦胆子油乳注射液联合放疗治疗骨转移癌疼痛完全缓解率61.8%(21/34),部分缓解率29.4%(10/34),总有效率91.2%(31/34),KPS评分较治疗前增加者占85.3%(29/34),随访1年生存率明显升高(P<0.05),白细胞计数减少较单纯放疗组也少(P<0.05)。结论:鸦胆子油乳注射液联合放疗治疗骨转移癌痛能增加疗效减轻毒副作用。

关 键 词:骨转移癌  疼痛  放射治疗  鸦胆子油乳注射液

METASTATIC BONE TUMOR PAIN TREATED WITH BRUCEA JAVANICA OIL EMULSION COMBINED WITH RADIOTHERAPY
LI Zhao-Yuan , YU Hai-Ying , NING Si-Qing , YI Tie-Nan. METASTATIC BONE TUMOR PAIN TREATED WITH BRUCEA JAVANICA OIL EMULSION COMBINED WITH RADIOTHERAPY[J]. Chinese Journal of Pain Medicine, 2012, 18(1): 35-37
Authors:LI Zhao-Yuan    YU Hai-Ying    NING Si-Qing    YI Tie-Nan
Affiliation:(Department of Oncology,Xiangyang center Hospital,Xiangyang 441021)
Abstract:Objective: To observe the clinical efficacy of treating metastatic bone tumor pain with injection of seminal oil emulsion plus radiotherapy.Methods: 66 patients with metastatic bone tumor were randomized into the observation group(n = 34) and the control group(n = 32).All of these patients were treated with radiotherapy DT = 30 Gy/10 F,the patients in the observation group were given additional emulsion of seminal oil of brucea javanica(10%,30 m1,1 time a day).Both were treated for 1 curative period of 21 days.Differences in the therapeutic efficacy,the quality of life index KPS,one year survival rate and hematologic-al toxicity during the treatment were observed.Results: The total effective rate in the observation group was significantly better than that in the control group(P < 0.05),the KPS and one year survival were better too,and hematological toxicity was lower.Conclusion: Treating with seminal oil emulsion injection plus radiotherapy improved curative effect and decreased toxicity on metastatic bone tumor.
Keywords:Metastatic bone tumor  Pain  Radiotherapy  Brucea javanica oil emulsion
本文献已被 CNKI 万方数据 等数据库收录!
点击此处可从《中国疼痛医学杂志》浏览原始摘要信息
点击此处可从《中国疼痛医学杂志》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号