18F-FDG肿瘤显像中心肌显影的研究

目的:观察~(18)F-FDG肿瘤显像患者中心肌显影的现象及心肌摄取与血糖水平的关系。方法:行~(18)F-FDG肿瘤显像的患者110例,年龄30～87岁,平均64.12±11.53岁。所有患者均空腹显像,胸部采集数据经默认条件处理后观察心脏显影程度。按照心肌显影程度分为4级:1级心肌完全不显影,2级心影高于纵隔影仅少部分清晰,3级心影高于纵隔影少于1/2心室,4级心肌完整显影。结果:72例男性中,心肌完全不显影26例,部分显影17例,完全显影29例,分别占36%,24%,40%,女性38例中,心肌完全不显影23例,部分显影8例,完全显影7例,分别占61%,21%,18%。各组心肌显影程度与空腹血糖(P值均>0.05)无明显关系。结论:肿瘤患者葡萄糖代谢显像心肌显影的程度各不相同,提示肿瘤惠者心肌葡萄糖代谢的复杂性。

Detect the Role of Myocardial Uptake in the 18F-FDG Tumor Imaging

Objective:To study the relationships of myocardial uptake ~(18)F-fluorodeoxyglucose(FDG)and the level of blood glucose in tumor imaging by a dual-head gamma camera operated in coincidence detection.Methods:The subjects included 110 patients with all kinds of cancers,~(18)F-FDG(370 MBq)was injected intravenously with fasting,each imaging was compare 18F- FDG uptake in the mediastinal or left ventricular cavity.The uptake degree of ~(18)F-FDG was divided four groups:1=no uptake; 2=uptake less but more than rnediastinal,3=uptake much and more than mediastinal,4=uptake of the left ventricular wall. Results:The degree of men no uptake,more uptake and uptake was 36%,24%,40%,The women' no uptake,more uptake and uptake was 61%,21%,18%,respectively.Conclusion:The degree of myocardial uptake ~(18)F-FDG are vary from each other and reflect the complexity of myocardial metabolism.