阴道超声引导下胚胎移植对于反复种植失败患者妊娠结局的影响

目的：探讨阴道超声引导下胚胎移植对于反复种植失败（repeated implantation failure, RIF）患者冻融胚胎移植妊娠结局的影响。方法：回顾性分析2017年6月至2019年6月，本中心进行IVF-ET（in vitro fertilization and embryo transfer）周期患者中，再次行冻融胚胎囊胚移植的48例RIF患者临床资料，根据胚胎移植时是否使用阴道超声引导下移植分为实验组（24例）和对照组（24例）。分析比较两组间的胚胎种植率、临床妊娠率及流产率。结果：实验组临床妊娠率（37.50%）和胚胎种植率（29.26%）均显著高于对照组（分别为29.16%、21.05%），差异具有统计学意义（P < 0.05）；流产率对照组（14.28%）和实验组（11.11%）无统计学差异（P > 0.05）。结论：采用阴道超声引导下胚胎移植可显著改善RIF患者的临床妊娠结局。

The effect of transvaginal ultrasound-guided embryo transfer on pregnancy outcome in patients with repeated implantation failure

Objective: To investigate the effect of transvaginal ultrasound-guided embryo transfer on the pregnancy outcome of patients with recurrent implantation failure (RIF). Methods: From June 2017 to June 2019, the clinical data of 48 RIF patients who underwent frozen thawed embryo transfer again were analyzed retrospectively. According to whether the embryo transfer was guided by transvaginal ultrasound, they were divided into experimental group (24 cases) and control group (24 cases). The clinical pregnancy rate, embryo implantation rate and spontaneous abortion rate between the two groups were analyzed and compared. Results: The clinical pregnancy rate (37.50%) of the experimental group and embryo implantation rate (29.26%) of the experimental group were significantly higher than those of the control group (29.16% and 21.05%, respectively), the difference was statistically significant (P < 0.05); the difference of the abortion rate of the control group (14.28%) and experimental group (11.11%) has no statistically significance (P > 0.05). Conclusion: Transvaginal ultrasound-guided embryo transfer can significantly improve the clinical pregnancy outcome of RIF patients.