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氦氖激光血管内照射对脑梗塞患者白细胞粘附功能等的影响
引用本文:赵仁亮,王春霞,李文健,王少萍,韩仲岩.氦氖激光血管内照射对脑梗塞患者白细胞粘附功能等的影响[J].中华理疗杂志,2001,24(1):17-19.
作者姓名:赵仁亮  王春霞  李文健  王少萍  韩仲岩
作者单位:1. 青岛医学院附属医院神经科
2. 青岛医学院第二附属医院神经科
摘    要:目的 观察低能量氦氖激光血管内照射(ILIB)对脑梗塞患者白细胞粘附功能(LAF)和血清可溶性细胞粘附分子-1(sICAM-1)水平的影响。方法 脑梗塞患者66例,30例单纯应用药物治疗(常规组),36例在药物治疗的基础上加用ILIB治疗(ILIB组)。检测两组患者治疗前、治疗后5,10d后LAF和血清sICAM-1浓度,并对患者治疗前后的临床神经功能缺损程度及临床疗效进行评价。结果 急性脑梗塞患者LAF和血清sICAM-1浓度明显高于正常对照组(t=16.50~17.94,P<0.001)。常规组治疗后LAF和血清sICAM-1浓度降低,仅在治疗10d时差异有非常显著性(t=3.18,P<0.01;t=3.96,P<0.001),而ILIB组治疗后5d及10d时LAF和血清sICAM-1浓度均明显降低(t=4.48~12.72,P<0.001),且明显低于同期常规组(t=2.67~7.81,P<0.01或0.001)。ILIB组比常规治疗组患者出现神经功能明显恢复的时间较早,治疗有效率高(χ2=4.48,P<0.05)。结论 ILIB能降低脑梗塞患者LAF和血清sICAM-1浓度,这可能是ILIB治疗脑梗塞的作用机制之一。

关 键 词:脑梗塞  氦氖激光血管内照射  激光疗法  白细胞粘附功能
修稿时间:1999年12月22

Effect of intravascular He-Ne laser irradiation on blood for leukocyte adhesion function and serum soluble intercellular molecule-1 in cerebral infarction patients
ZHAO Renliang,WANG Chunxia,LI Wenjian,et al..Effect of intravascular He-Ne laser irradiation on blood for leukocyte adhesion function and serum soluble intercellular molecule-1 in cerebral infarction patients[J].Chinese Journal of Physical Therapy,2001,24(1):17-19.
Authors:ZHAO Renliang  WANG Chunxia  LI Wenjian  
Institution:ZHAO Renliang,WANG Chunxia,LI Wenjian,et al. Department of Neurology,The Affiliated Hospital of Qingdao Medical College,Qingdao 266003,China
Abstract:Objective To investigate the effect of intravascular He-Ne laser irradiation on blood(ILIB) for leukocyte adhesion function(LAF) and serum soluble intercellular adhesion molecule-1(sICAM-1) in cerebral infarction(CT) patients. Methods  30 CI cases were treated with drug treatment(group A);other 36 cases,based on the drug treatment,received the ILIB therapy(group B) once a day for 10 times.another 40 healthy subjects were as control group.The LAF and sICAM-1 concentrations were measured before treatment and after the 5th and 10th day of treatment. Results The LAF and sICAM-1 concentrations in CI patients were obviously higher than those of control group(t=16.50~17.94,P<0.001).In group A,the LAF and sICAM-1 concentrations were significantly decreased in the 10th day after treatment(t=3.18,P<0.01;t=3.96,P<0.001),but,in group B,they presented on the 5th and 10th day after ILIB treatment(t=4.48~12.72,P<0.001).However,these parameters of group B were obviously lower than those of group A in the same stage(t=2.67~7.81,P<0.01 or 0.001).While the effective rate(72.22%) of group B was higher than that of group A(46.67%)(χ2=4.48,P<0.05). Conclusion These findings indicate that the ILIB therapy can decrease the LAF and sICAM-1 concentrations in CI patients and it is one of those mechanisms for treating CI patients probably.
Keywords:Laser  He-Ne  Cerebral infarction  Receptors  leukocyte-adhesion
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