维持性血液透析患者抑郁症状及其相关因素分析

目的调查维持性血液透析(maintenance hemodialysis,MHD)患者中抑郁症状发生情况并分析其相关因素,为提高患者生存质量提供依据。方法采用横断面调查,应用Zung抑郁自评量表(SDS)对复旦大学附属华山医院血液净化中心64例MHD患者进行评估,将患者分为存在抑郁症状组和无抑郁症状组,同时收集患者的一般临床资料、社会背景资料及实验室检查结果,进行统计分析,探讨抑郁症状及其相关因素。结果SDS的测定结果显示,MHD患者中抑郁症状的发生率为60.9%。抑郁症状组独身率、血清CRP水平明显高于无抑郁症状组(独身率:14/39比3/25,P<0.05;CRP(3.22±3.39)mg/L比(2.58±2.81)mg/L,P<0.05),而血红蛋白、血清白蛋白水平则显著偏低(血红蛋白:(101.0±18.7)g/L比(109.2±14.8)g/L,P<0.05;白蛋白(38.7±3.6)g/L比(40.5±2.7)g/L,P<0.05)。进一步进行多因素Logistic回归分析发现婚姻状况、血红蛋白水平是抑郁症状的主要相关因素,发生抑郁的概率方程LnP/(1-P)]=6.611+1.627X1-0....

Analysis on depressive symptoms and the related factors in maintenance hemodialysis patients

Objective We investigated the incidence of depression symptoms and the related factors in maintenance hemodialysis (MHD) patients,to understand the useful measures for the improvement of their life quality. Methods Sixty-four outpatients (male 24,female 40) with end-stage renal disease (ESRD) treated with MHD were recruited from the Dialysis Center of Huashan Hospital to participate in a cross-sectional study. Depression manifes-tations were assessed by Zung self-rating depression scale (SDS). If SDS score=...