原发胃黏膜相关淋巴组织淋巴瘤的外科治疗方式探讨

摘要】　目的 探讨原发胃黏膜相关淋巴组织(MALT)淋巴瘤的外科治疗方式。方法 回顾性分析总结39 例胃MAL T 淋巴瘤的外科治疗情况。结果 手术根治切除37 例, 姑息切除2 例, 术后加化疗11 例。随访30 例,全部为根治切除患者，随访率为76.9％，其中单纯手术组19例，术后化疗组11例。3例当年死亡，单纯手术组死亡2例，术后化疗组死亡1例；11 例存活3 年,，单纯手术组9例，术后化疗组2例, 总3年存活率36.37％； 8例存活5 年，单纯手术组5例，术后化疗组3例，总5年生存率26.67％；8例存活10年以上，单纯手术组3例, 术后化疗组5例，总10年生存率26.67％；11例术后采用CHOP方案化疗,其10年生存率达45.46％，明显高于单纯手术组的15.79%。结论 外科手术根治性切除原发灶，联合术后化疗和/ 或放疗比单纯手术切除可提高生存率。

Primary gastric mucosa-associated lymphoid tissue(MALT)lymphoma: a clinical analysis of 39 cases about its surgical treatment.

Abstract Objective To analyze the surgical treatment of the primary gastric mucosa-associated lymphoid tissue (MALT)lymphoma. Methods A retrospective analysis was done in 39 cases of gastric MALT lymphoma. Results Radical resection was given in 37 cases, palliative resection in 2 cases, chemotherapy after surgery in 11cases. Follow-up of 30 cases, follow-up rate is76.9%. Group of 19 patients were with surgery alone, 11 cases of postoperative chemotherapy group. 3 cases dead in that year, 11 cases survived 3 years, 8 cases survived 5 years, 8 patients survived more than 10 years. The total 10-year survival rate is 26.67％. 11 cases of postoperative patients used CHOP chemotherapy, and its 10-year survival rate was 45.46%, significantly higher than surgery alone group(15.79%) Conclusion Surgical resection of the primary tumor, combined with post-operative chemotherapy and / or radiotherapy may improve survival.