早发型重度子痫前期患者发病孕龄及终止妊娠时机对围产结局的影响

目的:探讨早发型重度子痫前期不同发病孕龄及终止妊娠时机对围产结局的影响。方法:回顾分析2002年1月至2007年12月广西医科大学第四附属医院115例早发型重度子痫前期患者的发病情况及妊振结局。按发病孕龄分3组,a组<28周,b组28～31+6周,c组32～33+6周。按终止妊娠孕周分为4组,A组<32周,B组32～33+6周,C组34～35+6周,D组≥36周。比较各组患者期待治疗的平均时间、并发症和围生儿病死率。结果:(1)a组围生儿病死率为87.5%,孕产妇并发症发生率为65.6%;b组围生儿病死率为38.5%,孕产妇并发症发生率为51.3%;c组围生儿病死率为11.4%,孕产妇并发症发生率为45.5%。随着发病孕龄的增加,围生儿病死率逐渐降低(P<0.05),3组患者并发症发生率随发病孕周增加而下降,但3组间比较差异无统计学意义(P>0.05)。(2)A组围生儿病死率为87.8%,孕产妇并发症发生率为58.5%。B组围生儿病死率为64.3%,孕产妇并发症发生率为46.4%。C组围生儿病死率为8.3%,孕产妇并发症发生率为52.8%。D组围生儿病死率为10.0%,孕产妇并发症发生率为50.0%。妊娠34...

Perinatal outcome of different onset gestation ages and different termination times of pregnancy in early onset severe preeclampsia

Abstract] Objective To study the effect of different onset gestation ages and different termination times of pregnancy in early onset severe preeclampsia on the perinatal outcomes. Methods A retrospective study was carried out on the condition of onset and pregnant outcome in 115 cases with early onset severe preeclampsia from January 2002 to October 2007. （1）The patients were divided into three groups accordingto the onset gestation ages：group a with a gestation age of less than 28 weeks, group b with a gestation age of 28-31+6weeks and group c with a gestation age of 32-33+6 weeks.（2）The patients were divided into four groups according to the termination times of pregnancy: group A with a termination time of less than 32 weeks, group B with a termination time of 32-33+6weeks,group C with a termination time of 34-35+6 weeks and group D with a termination time more than 36 weeks. Results （1）In group a, the perinatal infant mortality rate was 87.50%，rate of pregnant complications was 65.63%. In group b，the perinatal infant mortality rate was 38.46%，rate of pregnant complications was 51.28%. In group c，the perinatal infant mortality rate was 11.30%，rate of pregnant complications was 45.45%. Following the increase of gestation ages of onset, the perinatal infant mortality rate was decreased(P<0.05). The rate of pregnant complications was also decreased，but there was no significant diference among three groups(P＞0.05). （2）In group A, the perinatal infant mortality rate was 87.80%，rate of pregnant complications was 58.53%. In group B，the perinatal infant mortality rate was 64.29%，rate of pregnant complications was 46.43%. In group C，the perinatal infant mortality rate was 8.33%，rate of pregnant complications was 52.78%. In group D，the perinatal infant mortality rate was 10.00%，rate of pregnant complications was 50.00%.Before the termination times of 34 weeks,following the increase of termination times of pregnant, the perinatal infant mortality rate was decreased(P<0.05). The rate of pregnant complications among the four groups there was no significant diference (P＞0.05). Conclusion The earlier the onset of severe preeclampsia, the higher of perinatal infant mortality rate.Expectant treatment for severe preeclampsia occurring in more than 28 gestation weeks can significantly prolong the gestation weeks and improve the perinatal outcome.