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Cryoglobulinemia and fibronectin in systemic lupus erythematosus
Authors:A A Baranauska?te  E L Nasonov  E E Efremov  L V Kurmanova  M V Eremeeva  S K Solov'ev  V Iu Kovalev  O V Lopaeva  A G Kobylianski?
Abstract:EIA was used to measure the concentration of fibronectin in plasma and cryoprecipitates of 37 patients suffering from systemic lupus erythematosus coupled with cryoglobulinemia. A definite relationship was discovered between the level of cryoglobulins and the activity of SLE, the concentration of fibronectin in plasma and liver damage. A tendency was revealed towards increase of the fibronectin content in plasma of patients with a high level of antibodies to native DNA and CIC as was a significant correlation between the concentration of cryoglobulin protein and the concentration of fibronectin in cryoprecipitates.
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