| 高强度聚焦超声对肝癌患者免疫功能的影响 |
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| 引用本文： | 高远,王凤鸣,冯军,王宇岭.高强度聚焦超声对肝癌患者免疫功能的影响[J].山西临床医药,2009(35):2236-2237. |
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| 作者姓名： | 高远 王凤鸣 冯军 王宇岭 |
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| 作者单位： | 江苏省苏州大学附属第一医院肿瘤科;江苏省苏州大学医学生物技术研究所 |
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| 摘 要： | 目的:探讨高能聚焦超声(high intensity focused ultrasound,HIFU)治疗后肝癌患者免疫功能的变化。方法:应用FEP-BY01型肿瘤超声治疗机对36例原发性肝癌患者进行治疗;分别取HIFU治疗前和HIFU治疗后4w外周血2ml,检测T细胞亚群CD4、CD8、CD4/CD8及NK细胞。结果:治疗后NK细胞百分数、CD4T细胞百分数、CD4/CD8比值较治疗前明显升高,而CD8T细胞百分数下降。结论:应用HIFU技术治疗原发性肝癌可以改善患者体内的细胞免疫功能。
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| 关 键 词： | 高强度聚焦超声 肝癌 免疫 |
The effect of high intensity focused ultrasound on immunity in the patients with primary hepatocellular carcinoma |
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| Gao Yuan,Wang Fengming,FengJun,Wang Yuling.The effect of high intensity focused ultrasound on immunity in the patients with primary hepatocellular carcinoma[J].Shanxi Clinical Medicine,2009(35):2236-2237. |
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| Authors: | Gao Yuan Wang Fengming FengJun Wang Yuling |
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| Institution: | 1.Cancer Center, the Affiliated First Hospital; 2. Institute of Medical Biotechnology, Soochow University, Suzhou 215006, China) |
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| Abstract: | Objective: To investigate immunity in patients with hepatocellular carcinoma treated by high intensity focused ultrasound (HIFU) treatment. Methods:Thirty-six patients with hepatocellular carcinoma were treated by HIFU.The percentage of natural killer cells and T-lymphocyte subsets CD4、CD8、 CD4/CD8 in 2 mL of peripheral venous blood were examined before and four weeks after HIFU treatment.Results: The posttreatment levels of CD4、CD4/CD8 and NK were much higher than those before treatment.Whereas the levels of CD8 were significantly lower than those before treatment.Conclusion:HIFU treatment of the patients with hepatocellular carcinoma improved the Cellular immune function. |
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| Keywords: | High intensity focused ultrasound hepatocellular carcinoma immunology |
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