| 组织局部RAAS与2型糖尿病慢性合并症 |
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| 引用本文： | 李季,杜群.组织局部RAAS与2型糖尿病慢性合并症[J].现代诊断与治疗,2009,20(1):40-42. |
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| 作者姓名： | 李季 杜群 |
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| 作者单位： | 内蒙古科技大学包头医学院,内蒙古,包头,014030 |
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| 摘 要： | 局部肾素-血管紧张素-醛固酮系统(RAAS)是指血管紧张素Ⅱ(AngⅡ)不是来自循环而是由特殊组织产生,其产生的AngⅡ并不作用于远处,而是直接作用于局部或其邻近组织。RAAS广泛存在于包括肾脏、胰腺、心脏、视网膜等多种器官和组织。近年来大量研究表明,糖尿病患者局部RAAS水平升高,且与糖尿病肾病、糖尿病视网膜病变等密切相关。
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| 关 键 词： | 组织局部 肾素-血管紧张素-醛固酮系统 血管紧张素Ⅱ 2型糖尿病 |
Renin-Angiotensin-Aldosterone System of Local Organizations and Chronic Complications of Type 2 Diabetes |
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| LI Ji,DU Qun.Renin-Angiotensin-Aldosterone System of Local Organizations and Chronic Complications of Type 2 Diabetes[J].Modern Diagnosis & Treatment,2009,20(1):40-42. |
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| Authors: | LI Ji DU Qun |
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| Institution: | ( Baotou Medical College, Scientific and Techological University of Inner Mongolia, Baotou 014030, China) |
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| Abstract: | Local renin-angiotensin-aldosterone system（RAAS） means that the angiotensin Ⅱ （Ang Ⅱ ） is not from the cycle but is produced by special organizations. Ang Ⅱ does not act on the remote,but rather acts on local or nearly organizations directly. RAAS widly exists in kidney, pancreas, heart, retina and other organs and tissues. In recent years, a large number of studies have shown that local RAAS level increases in diabetic patients,and is closely related to diabetic nephropathy and diabetic retinopathy. |
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| Keywords: | Local organizations RAAS Angiotensin Ⅱ Tape 2 diabetes mellitus |
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