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Barrett食管与胃食管反流病及食管腺癌的关系
引用本文:李治仝,汪忠镐,季锋,高翔,张成超,胡志伟,宁雅婵.Barrett食管与胃食管反流病及食管腺癌的关系[J].临床误诊误治,2011,24(11):10-13.
作者姓名:李治仝  汪忠镐  季锋  高翔  张成超  胡志伟  宁雅婵
作者单位:1. 首都医科大学北京宣武医院血管外科, 北京,100053
2. 100088 北京,解放军第二炮兵总医院胃食管反流中心;100053 北京,首都医科大学北京宣武医院血管外科
3. 北京航空总医院胃食管反流中心, 北京,100012
基金项目:国家863高技术研究发展计划资助项目(2007AA0Z4Z6)
摘    要:胃食管反流(gastroesophageal reflux,GER)在人群中普遍存在,Barrett食管(Barrett’s esophagus,BE)及食管腺癌(esophageal adenocarcinoma,EA)的发病率也在逐年升高。为了解BE与胃食管反流病(gastroesophageal reflux dis-ease,GERD)、EA的关系,本文复习近年相关文献,从病理生理基础及诊断、治疗方法入手进行探讨,结果发现三者的病情进展过程为正常食管黏膜-GERD-BE化生-BE低度和高度异型增生-EA。故BE的治疗应以减轻GER症状为主,并定期筛检和评价预后,以早期发现EA。

关 键 词:Barrett食管  胃食管反流  腺癌  食管

The Relationship between Barrett's Esophagus and Gastroesophageal Reflux Disease,Esophageal Adenocarcinoma:Literature Review
LI Zhi-tong,WANG Zhong-gao,JI Feng,GAO Xiang,ZHANG Cheng-chao,HU Zhi-wei,NING Ya-chan.The Relationship between Barrett's Esophagus and Gastroesophageal Reflux Disease,Esophageal Adenocarcinoma:Literature Review[J].Clinical Misdiagnosis & Mistherapy,2011,24(11):10-13.
Authors:LI Zhi-tong  WANG Zhong-gao  JI Feng  GAO Xiang  ZHANG Cheng-chao  HU Zhi-wei  NING Ya-chan
Institution:LI Zhi-tong1,WANG Zhong-gao1,2,JI Feng3,GAO Xiang1,ZHANG Cheng-chao1,HU Zhi-wei1,NING Ya-chan1(1.Cardiovascular Surgery,Xuan Wu Hospital,Capital Medical University,Beijing 100053,China,2.Department of Gastroesophageal Reflux,General Hospital of the Second Artillery Troops of PLA,Beijing 100088,3.Department of Gastroesophageal Reflux,General Hospital of Astronautics of Beijing,Beijing 100012,China)
Abstract:Gastroesophageal reflux is widespread in the population,the incidence rate of Barrett's esophagus(BE) and esophageal adenocarcinoma(EA) is rising year by year.In order to learn the relationship between BE,GERD and EA,this article reviewed the related literature of recent years,focusing on pathophysiology,diagnosis and treatments.The results showed three of the disease progression from normal esophageal mucosa,GERD,BE metaplasia,BE low and high hyperplasia to EA.In view of this,the treatment of BE should aim...
Keywords:Barrett's esophagus  Gastroesophageal reflux  Adenocarcinoma  Esophagus  
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