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家兔颈淋巴引流阻断后脑组织含水量、Ca2+及SOD的变化
引用本文:高宇飞,赵勇,杨占泉.家兔颈淋巴引流阻断后脑组织含水量、Ca2+及SOD的变化[J].中国实验诊断学,2007,11(3):350-352.
作者姓名:高宇飞  赵勇  杨占泉
作者单位:1. 吉林大学中日联谊医院,神经外科,吉林,长春,130033
2. 吉林省洮南市医院,外三科,吉林,洮南,137100
3. 吉林大学中日联谊医院,耳鼻咽喉-头颈外科,吉林,长春,130033
摘    要:目的探讨家兔颈淋巴引流阻断后,脑组织含水量、钙及超氧化物歧化酶含量的变化及其意义。方法将50只新西兰白兔随机分为实验组和对照组,实验组行颈淋巴管结扎、淋巴结清扫术,对照组行假手术。两组分别于术后24h,48h,72h,96h,168h等五个时间点,进行脑组织含水量、钙及超氧化物歧化酶含量测定。结果家兔颈淋巴引流阻断后,脑组织含水量、钙含量明显增高,超氧化物歧化酶含量明显下降。结论家兔颈淋巴引流阻断后,引起脑淋巴回流阻滞,产生淋巴滞留性脑水肿。

关 键 词:    淋巴  超氧化物歧化酶
文章编号:1007-4287(2007)03-0350-03
收稿时间:2006-06-16
修稿时间:2006年6月16日

The change of contents of water, ealcium and superoxide dismutase in rabbit brain after obstruction of cervical lymphatic drainage
GAO Yu-fei,ZHAO Yong,YANG Zhang-quan.The change of contents of water, ealcium and superoxide dismutase in rabbit brain after obstruction of cervical lymphatic drainage[J].Chinese Journal of Laboratory Diagnosis,2007,11(3):350-352.
Authors:GAO Yu-fei  ZHAO Yong  YANG Zhang-quan
Abstract:Objective To investigate the signification of the change of contents of water,calcium and superoxide dismutase in rabbit brain after obstruction of cervical lymphatic drainage.Methods Fifty New Zealand white rabbits were randomized into two groups:experiment group and control group.The rabbits in experiment group underwent ligation of cervical lymphatic vessel and clearance of lymph nods.The other group underwent mimic operation.At the point of 24h,48h,72h,96h and 168h after operation we measured contents of water,calcium and superoxide dismutase in rabbit brain.Results The contents of water,calcium in rabbit brain were increased significantly after obstruction of cervical lymphatic drainage.On the other hand,the contents of superoxide dismutase decreased markedly.Conclusion The obstruction of cerebral lymphatic drainage occurred after obstruction of cervical lymphatic drainage.That brought lymphatic cerebroedema.
Keywords:rabbits  brain  lymph  superoxide dismutase
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