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The study on change of serum cytokines levels and its correlation with function rehabilitation in patients with cerebral infarction
Authors:LI Zuo -xiao  CHEN Xiu  TAN Hua  XIONG Xian -ji  PENG Jian -yi
Abstract:ObjectiveTo understand the pathogenetic role and clinical significance of interleukin 6(IL -6),tumor necrosis factor(TNF)and soluble interleukin -2receptor(sIL -2R)in patients with cerebral infarctio n(CI ).MethodsThe IL -6,TNF and sIL -2R levels were measured in 46CI patient s with ELISA.ResultsThe serum IL -6,TNF and sIL -2R levels of CI group were much higher than those of controls group .The variation of IL -6,TNF and sIL -2R levels was c losely related to the size of cerebra l infarction.The serum IL -6,TNF and sIL -2R levels of recovery p eriod were much lower than those of acute period in patients with CI .Conclusions The IL -6,TNF and sIL -2R take part in the pathologi c process after CI .The measurement o f IL -6,TNF and sIL -2R is useful in determining the size of cerebral infarction.
Keywords:cerebral infarction  interleukin 6  tumor necrosis factor  soluble int erleukin -2receptor
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