| 司帕沙星与洛美沙星片剂临床疗效及安全性的比较 |
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| 引用本文： | 殷凯生,李梅梅,许志超,蔡健康.司帕沙星与洛美沙星片剂临床疗效及安全性的比较[J].实用临床医药杂志,1999(1). |
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| 作者姓名： | 殷凯生 李梅梅 许志超 蔡健康 |
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| 作者单位： | 南京医科大学第一附属医院!南京，210009(殷凯生，李梅梅)，南京医科大学第二附属医院!南京，210009(许志超，蔡健康) |
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| 摘 要： | 目的：评价抗菌新药司帕沙星片剂的临床疗效及安全性。方法：以洛美沙星片剂为对照，在73例急性细菌性感染患者中进行随机对照性研究。结果：试验组的痊愈率（84.21%）、有效率（92.11%）均高于对照组的痊愈率（65.71%）和有效率（82.86%），但统计学差异无显著性（P＞0.05）。试验组患者不良反应发生率（5．3%）显著低于对照组（14.3%），P＜0.05。结论：在细菌感染性疾病的治疗中，司帕沙星片剂优于洛美沙星片剂。
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| 关 键 词： | 司帕沙星 洛美沙星 疗效 安全性 |
A COMPARISON ON CLINICAL EFFICACY AND SAFETY OF SPARFLOXACIN AND LOMEFLOXACIN |
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| Yin Kaisheng, Xu Zhicao, Li Meimei,et al..A COMPARISON ON CLINICAL EFFICACY AND SAFETY OF SPARFLOXACIN AND LOMEFLOXACIN[J].Journal of Clinical Medicine in Practice,1999(1). |
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| Authors: | Yin Kaisheng Xu Zhicao Li Meimei |
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| Institution: | Yin Kaisheng; Xu Zhicao; Li Meimei; et al. |
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| Abstract: | Aim: to evaluate the clinical efficacy and safety of Sparfloxacin tablets, a random con-trast study compared with Lomefloxacin tablts in 73 patients with acute infections caused by bacteria wasperformed. Result: the recovered rate (84. 21 % ) and effective rate (92. 11 % ) in the test group werehigher than the recovered rate (65. 71 % ) and effective rate (82. 86% ) in the contrast group, thoughthere were no significant differance statistically (P >O. O5). The side - effetive rate was 5. 3% in thetest group, which was lower than that (14. 3% ) in control group (P < 0. 05 ). Conclusion:Sparfloxacin tablets are better than Lomefloxacin tablets in treating acute infectious-diseases caused by bac-teria. |
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| Keywords: | Sparfloxacin Lomefloxacin efficacy safety |
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