基于CLHLS项目2018年横断面数据的高龄人群高血压、糖尿病患病率及相关因素研究

目的分析中国高龄人群高血压、糖尿病患病情况以及高血压合并糖尿病的相关因素。方法获取中国老年健康影响因素跟踪调查(CLHLS)2018年横断面数据,计算高血压、糖尿病患病率及服药治疗率,分析患病率及服药治疗率的性别、年龄差异,并采用有序多结局Logistic回归分析的比值比(OR)及其95%置信区间(95%CI)评估性别、年龄及地域差异与高龄人群患高血压合并糖尿病的相关性。结果纳入研究对象15874例,平均年龄为(85.46±11.70)岁,男性占43.62%。高血压、糖尿病患病率及高血压与糖尿病共患率分别为42.93%(95%CI为42.13%~43.74%)、10.14%(95%CI为9.64%~10.64%)和7.49%(95%CI为7.05%~7.92%)。女性高血压和糖尿病患病率均高于男性,差异有统计学意义(P<0.05)。高血压服药治疗信息缺失率大于30%,糖尿病服药治疗信息缺失率大于50%。随着年龄增长,高血压和糖尿病患病率均呈下降趋势,差异有统计学意义(P<0.05)。百岁以上老人的高血压、糖尿病患病率分别为25.91%(95%CI为23.88%~27.93%)和2.14%(95%CI为1.45%~2.82%)。有序三结局Logistic回归分析结果显示,男性、大于90岁、居住在北方是高龄人群高血压合并糖尿病的保护因素(P<0.05)。结论高龄群体高血压、糖尿病的分布存在性别差异,患病率随着年龄增长而降低,高血压合并糖尿病与性别、年龄及地域均有关联。

Research on prevalence rate and related factors of hypertension and diabetes in senile people based on cross-sectional data of CLHLS study in 2018

Objective To analyze prevalence of hypertension and diabetes in senile people in China and related factors of hypertension complicated with diabetes.Methods Cross-sectional data of 2018 in Chinese Longitudinal Healthy Longevity Survey(CLHLS)were collected for calculation of prevalence rate and medication therapeutic rate of hypertension and diabetes.Differences of prevalence and therapeutic rates in gender and age were analyzed,and odds ratio(OR)and its 95%confidence interval(95%CI)in ordered multiple outcomes Logistic regression analysis were used to evaluate the correlations between differences of gender,age,geographic region and hypertension complicated with diabetes.Results A total of 15874 participants were selected,with an average age of(85.46±11.70)years,and 43.62%participants were male.Prevalence rates of hypertension,diabetes and hypertension complicated with diabetes were 42.93%(95%CI was from 42.13%to 43.74%),10.14%(95%CI was from 9.64%to 10.64%)and 7.49%(95%CI was from 7.05%to 7.92%),respectively.Prevalence rates of hypertension and diabetes in female were significantly higher than those in male(P<0.05).Missing rate of medication information for hypertension was higher than 30%,and missing rate of medication information for diabetes was higher than 50%.Prevalence rates of hypertension and diabetes decreased significantly with increasing of age(P<0.05).Prevalence rates of hypertension and diabetes in people aged over 100 years were 25.91%(95%CI was from 23.88%to 27.93%)and 2.14%(95%CI was from 1.45%to 2.82%),respectively.Ordinal three-outcome Logistic regression analysis showed that male,aged over 90 years,living in northern part of China were protective factors for hypertension complicated with diabetes in senile people(P<0.05).Conclusion There are differences in gender in the distributions of hypertension and diabetes in senile people.Prevalence rates of hypertension and diabetes decrease with increasing of age,and hypertension complicated with diabetes are associated with gender,age and geographic region.