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| 缺血性脑卒中相关危险因素的病例对照研究 | |
| 引用本文： | 孙昊,吴昊,栾春业,陆莹,王军,季晨博,陈彦,肖杭,张劲松.缺血性脑卒中相关危险因素的病例对照研究[J].实用临床医药杂志,2010,14(1):32-35. |
| 作者姓名： | 孙昊 吴昊 栾春业 陆莹 王军 季晨博 陈彦 肖杭 张劲松 |
| 作者单位： | 1. 南京医科大学第一附属医院,急诊中心,江苏,南京,210029 2. 南京医科大学公共卫生学院流行病与卫生统计学系,江苏,南京,210029 3. 南京医科大学公共卫生学院神经毒理实验室,江苏,南京,210029 4. 南京医科大学附属南京妇幼保健院,江苏,南京,210000 |
| 基金项目： | 江苏省科技厅的社会发展重点项目 |
| 摘 要： | 目的评价传统与新型相关危险因素与缺血性脑卒中发病风险的关系。方法采用病例对照研究方法,在华东地区选择401例缺血性脑卒中病例,其中脑血栓形成158例,腔梗243例。和442例正常对照组人群。用问卷调查和体检的方式对缺血性脑卒中相关因素进行收集和分析。结果单因素分析显示:BMI,脑血管病家族史,既往史中的TIA、高血压、糖尿病、冠心病、肾脏疾病,目前血压值(包括收缩压和舒张压),血常规中的白细胞数、中性粒细胞比例,生化指标中的血糖、TG、HDL-C值均提示能增加缺血性脑卒中的发病风险(P0.05)。Logistic回归分析显示:TIA史、高血压、糖尿病、冠心病等既往史能显著增加缺血性脑卒中的患病风险。结论缺血性脑卒中需要采取综合干预措施。新的危险因素不容忽视。影响疾病发生发展的其它危险因素尚需要进一步探讨。 |
| 关 键 词： | 缺血性脑卒中 危险因素 病例对照研究 |
A case-control study of risk factors for ischemic stroke |
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| SUN Hao,WU Hao,LUAN Chun-ye,LU Ying,WANG Jun,JI Chen-bo,CHEN Yan,XIAO Hang,ZHANG Jin-song.A case-control study of risk factors for ischemic stroke[J].Journal of Clinical Medicine in Practice,2010,14(1):32-35. | |
| Authors: | SUN Hao WU Hao LUAN Chun-ye LU Ying WANG Jun JI Chen-bo CHEN Yan XIAO Hang ZHANG Jin-song |
| Institution: | SUN Hao1,WU Hao1,LUAN Chun-ye1,LU Ying3,WANG Jun2,JI Chen-bo4,CHEN Yan1,XIAO Hang2,ZHANG Jin-song1(1.Department of Emergency,First Affiliated Hospital of Nanjing Medical University,Nanjing,210029,2.Laboratory of Neurotoxicology,School of Public Health,Nanjing Medical University,3.Department of Epidemiology , Biostatistics,4.Affiliated Meternal , Child Health Hospital of Nanjing Medical University,210029) |
| Abstract: | Objective To evaluate the relationship between traditional and new risk factors and ischemic stroke.Methods The case-control study chose 401 cases(158 cerebral thrombosis,243 lacunar infarction) and 442 controls from East China.The related factors were collected and analyzed by questionnaire and health examination,and all controls were matched according to gender,age and region.Results one-way analysis of variance showed that BMI,family history of cerebrovascular disease,transient ischemic attack(TIA),hyper... |
| Keywords: | ischemic stroke risk factors case-control study |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |