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Direct oral anticoagulant (DOAC) reversal: Andexxa versus 4 factor prothrombin concentrates
Institution:1. Department of Pathology and Laboratory Medicine, Medical Sciences I, Room D440, University of California, Irvine, Irvine, CA 92697-4800, USA;2. Université de Paris, Laboratoire de Biologie Physico-Chimique des Protéines Membranaires, CNRS, UMR 7099, F-75005 Paris, France;3. Institut de Biologie Physico-Chimique, Fondation Edmond de Rothschild pour le développement de la recherche scientifique, F-75005 Paris, France;4. Department of Molecular Biology and Biochemistry, Department of Pharmaceutical Sciences, 1218 Natural Sciences, University of California, Irvine, Irvine, CA 92697-3900, USA;1. Department of Medicine, Infectious Disease Clinical Outcomes Research (ID-CORE), LA Biomed at Harbor-UCLA Medical Center, Torrance, CA, USA;2. Los Angeles County Department of Public Health, Healthcare Outreach Unit, Los Angeles, CA, USA;3. Expert Stewardship, Newport, CA, USA;4. Division of Infectious Diseases, Department of Medicine, University of California Irvine School of Medicine, Irvine, CA, USA;5. University of Massachusetts Amherst School of Public Health and Health Sciences, Amherst, MA, USA;6. Hoag Hospital, Newport, CA, USA;7. Department of Pathology and Laboratory Medicine, University of California, Irvine School of Medicine, Irvine, CA, USA;8. Division of Geriatrics, Department of Medicine, University of California Irvine, Orange, CA, USA;9. Department of Health Services, Policy and Practice, Brown University School of Public Health, Providence, RI, USA;10. Center of Innovation in Long-Term Services and Supports, Veterans Affairs Medical Center, Providence VA Medical Center, Providence, RI, USA;11. Center for Long-Term Care Quality and Innovation, Brown University School of Public Health, Providence, RI, USA;12. Cook County Health and Hospitals System, Chicago, IL, USA;13. Department of Medicine, Rush University Medical Center, Chicago, IL, USA;14. Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA;15. California Association of Long Term Care Medicine, Santa Clarita, CA, USA;p. The National Association of Directors of Nursing Administration in Long Term Care, Springdale, OH, USA;q. California Association of Health Facilities, Sacramento, CA, USA;r. Department of Medicine, Health Policy Research Institute, University of California Irvine School of Medicine, Irvine, CA, USA;1. Department of Microbiology, Immunology & Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA;2. Vaccine Research Laboratory, UBC Centre for Disease Control, University of British Columbia, Vancouver, BC V5Z 4R4, Canada;3. Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA 92697, USA;4. Department of Pediatrics, University of North Carolina–Chapel Hill, Chapel Hill, NC 27599-7509, USA;5. Division of Microbiology and Infectious Diseases, NIAID, Bethesda, MD, USA;1. Department of Medicine, Division of Hematology-Oncology, University of California Irvine School of Medicine, Orange, CA 92868, United States;2. Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA 92868, United States;3. Foundation Medicine Inc., 150 Second Street, Cambridge, MA 02141, United States;4. Department of Pathology and Laboratory Medicine, Albany Medical Center, Albany, NY 12208, United States;5. USC Norris Comprehensive Cancer Center and Hospital, Department of Medicine, Division of Medical Oncology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, United States
Abstract:
Keywords:Andexanet  Anticoagulant reversal  Complication of anticoagulation  Bleeding
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