| SLE和皮肌炎患者下丘-垂体-甲状腺轴的研究 |
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| 引用本文： | 李峰,冯树芳,徐金华,黄岚,邓守真.SLE和皮肌炎患者下丘-垂体-甲状腺轴的研究[J].临床皮肤科杂志,2000,29(2):73-75. |
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| 作者姓名： | 李峰 冯树芳 徐金华 黄岚 邓守真 |
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| 作者单位： | 1. 上海医科大学华山医院皮肤科,200040
2. 上海医科大学华山医院核医学科 |
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| 基金项目： | 国家自然科学基金!资助项目 ( 3 9770 688) |
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| 摘 要： | 应用促甲状腺激素释放激素（ＴＲＨ）兴奋试验探讨３４例ＳＬＩ活动期患者、１３例ＳＬＥ静止期和８例皮肌炎患者下丘－垂体、甲状腺轴活动。结果显示，ＳＬＥ活动期血清促甲状腺激素（ＴＳＨ）和催乳素（ＰＲＬ）水平在０、１５、３０、６０分钟和１２０分钟与正常对照组及ＳＬＥ静止期比较显著升高，而静止校无显著性差异’；皮肌炎在０、１５、３０、６０分钟及１２０分钟与正常组比较有显著性差异，而皮肌炎各时点表ＴＳＨ水平与
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| 关 键 词： | 系统性红斑狼疮 皮肌炎 下丘－垂体－甲状腺轴 |
Study on the hypothalamic- pituitary- thyroidal axis function in SLE and dermatomyositis |
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| Li Feng,Feng Shufang,Xu jinhua,Huang Lan,Den Shouzhen.Study on the hypothalamic- pituitary- thyroidal axis function in SLE and dermatomyositis[J].Journal of Clinical Dermatology,2000,29(2):73-75. |
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| Authors: | Li Feng Feng Shufang Xu jinhua Huang Lan Den Shouzhen |
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| Abstract: | To study the hypothalamic pituitary thyroidal axis function in 34 patients with active SLE, 13 patients with inactive SLE,8 patients with dermatomyositis(DM),and the results were compared with 10 gender age paired control subjects The basal serum prolactin(PRL) level (0 min) and at 15 min, at 30 min, at 60 min, at 120 min, after TRH injection in active SLE were significantly higher than those of inactive SLE and control subjects The basal serum thyrotropin(TSH) level (0min ) and at 15 min, at 30 min,at 60 min, at 120 min after TRH injection in DM were significantly different from control subjects,, but not significantly different from inactive and active patients of SLE It indicated that the TSH and PRL in active SLE and DM responded increasingly to TRH |
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| Keywords: | Lupus erythematosus systemic Dermatomyositis Thyrotropin releasing hormone |
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