Partial repigmentation of vitiligo with tofacitinib,without exposure to ultraviolet radiation |
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Institution: | 1. School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil;2. School of Medicine, Universidade do Vale do Itajaí, Itajaí, SC, Brazil;3. Private Rheumatology Clinic, Curitiba, PR, Brazil;4. Department of Dermatology, Faculdade de Medicina, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil |
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Abstract: | Vitiligo is a disease that causes macules and achromic and/or hypochromic patches, which can affect from small areas to the entire tegument. Treatment options are few and are generally ineffective. Recently, some case reports have appeared which show positive results with the use of Janus kinase inhibitors associated with phototherapy. This report details the case of a patient with rheumatoid arthritis associated with vitiligo in treatment for two years, whose condition partially improved initially after eight months of oral tofacitinib at a dose of 5 mg twice a day, without exposure to ultraviolet radiation and with continuous improvement during these two years of treatment. |
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Keywords: | Janus kinases Phototherapy Vitiligo |
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