眉部瘢痕性红斑一例

患者男，12岁，眉、颊部红斑、毛囊性丘疹7年。以眉部红斑、毛囊性丘疹起病，渐蔓延至颊部、前额，后逐渐出现眉毛脱落，无瘙痒等不适。体检：眉部、前额、颊部暗红色斑片，边界尚清，其上有针头至米粒大小毛囊性丘疹，表面光滑，质稍硬，眉毛大部分脱落。皮损组织病理检查：毛囊口扩大，毛囊角栓，真皮浅层胶原纤维增粗、硬化，血管、毛囊周围少量淋巴组织细胞浸润。根据临床表现及皮肤组织病理，诊断为眉部瘢痕性红斑。治疗：口服维生素A 2.5万U每日1次，维生素E 100 mg每日1次，外用维生素E乳膏每日2次，0.025%维A酸软膏每晚1次。治疗2周后皮损改善。

Ulerythema ophryogenes: a case report

A case of ulerythema ophryogenes （UO） is reported. A 12-year-old boy presented with erythema and follicular papules on the eyebrows and cheeks for 7 years. The lesions started as follicular papules surrounded by erythema, then spread symmetrically to the cheeks and forehead followed by the loss of eyebrows. There was no complaint of pruritus. Physical examination showed pinhead- to grain-sized, smooth, slightly indurated follicular hyperkeratotic papules surrounded by erythematous halo on the eyebrows, forehead and cheeks. Both eyebrows were nearly completely lost. Histological analysis of lesions from eyebrows revealed dilated follicular infundibulum with orthokeratotic plugs, sparse perivascular and perifollicular lymphohistiocytic infiltrate, widened and sclerotic collagen fibers in the dermis. According to the clinical manifestations and histopathological findings, the patient was diagnosed with ulerythema ophryogenes, and given oral vitamin A 2.5 million unit once a day, vitamin E 100 mg once a day, topical vitamine E cream twice a day, 0.025% tretinoin ointment once at night. Two weeks later, the lesions improved.