自主神经在特应性皮炎免疫失调中的作用

【摘要】 皮肤含有丰富的神经末梢，其中自主神经与皮肤角质形成细胞、免疫细胞间均存在密切的交互联系，对皮肤生理功能具有重要的调控作用。特应性皮炎患者皮损自主神经密度减少，同时伴有泌汗障碍等自主神经功能异常。通过恢复自主神经功能，可改善特应性皮炎症状。本文综述皮肤自主神经的结构和生理功能、特应性皮炎患者自主神经功能异常的表现以及可能的治疗策略。

Role of the autonomic nervous system in immune imbalance in atopic dermatitis

【Abstract】 The skin is rich in nerve terminals, among which autonomic nerves closely interacted with keratinocytes and immune cells. The autonomic nerves are critical to skin physiological function. Patients with atopic dermatitis exhibit reduced autonomic innervation, accompanied by autonomic nerve dysfunction such as sweating disorder. Restoration of autonomic neurological function can ameliorate atopic dermatitis. This review summarizes the anatomy and physiological function of skin autonomic nerves, autonomic neurological abnormalities in atopic dermatitis, and possible therapeutic strategies.