Dermatology Unit, Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico di Milano, Università degli Studi di Milano, Milan, Italy;3. Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA;4. Department of Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA;5. Clinical Dermatology Department, IRCCS S. Gallicano Dermatological Institute, Rome, Italy;6. School of Public Health, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy;7. Ben Gurion University of the Negev, Beer Sheva, Israel