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米非司酮与桂枝茯苓胶囊联合治疗子宫肌瘤临床疗效及安全性研究
引用本文:余霞.米非司酮与桂枝茯苓胶囊联合治疗子宫肌瘤临床疗效及安全性研究[J].中国性科学,2012(9):29-31,88.
作者姓名:余霞
作者单位:广西壮族自治区南溪山医院妇产科,广西 桂林 541002
摘    要:目的:探讨米非司酮与桂枝茯苓胶囊联合治疗子宫肌瘤的临床疗效及安全性.方法:将2011年3月~2012年3月在我科接受治疗的92例子宫肌瘤患者分为观察组和对照组各46例,对照组给予米非司酮口服治疗,观察组给予米非司酮联合桂枝茯苓胶囊治疗,观察两组患者治疗前后肌瘤及子宫体积变化情况及性激素水平变化情况,并进行疗效评价.结果:观察组治疗后肌瘤及子宫体积明显小于对照组(P<0.05);观察组治愈率及总有效率明显高于对照组(P<0.05);观察组治疗后 E2及 P水平明显低于对照组(P<0.05);两组不良反应均较轻微,且发生率比较无显著差异(P<0.05).结论:米非司酮与桂枝茯苓胶囊联合治疗子宫肌瘤具有疗效好,见效快,不良反应少等诸多优点,可作为目前治疗子宫肌瘤的一种较佳保守治疗方案.

关 键 词:子宫肌瘤  米非司酮  桂枝茯苓胶囊  性激素水平

Effect and safety of mifepristone combined with Guizhifuling capsule on the treatment of uterine fibroids
YU Xia.Effect and safety of mifepristone combined with Guizhifuling capsule on the treatment of uterine fibroids[J].The Chinese Journal of Human Sexuality,2012(9):29-31,88.
Authors:YU Xia
Institution:YU Xia Department of Obstetrics and Gynaecology,Nanxishan Hospital of Guangxi Zhuang Autonomous Region,Guilin 541002,China
Abstract:Objectives: To investigate the clinical efficacy and safety of Mifepristone combined with Guizhifuling capsule on the treatment of uterine fibroids.Methods: A total of 92 patients with uterine fibroids treated in our hospital from March 2011 to March 2012 were divided into the observation group and the control group,with 46 patients in each group.The control group was given mifepristone treatment,while the observation group was treated with Mifepristone combined with Guizhifuling capsule.The curative efficacy was evaluated by observing the changes of myoma size,uterine volume and sex hormone level in the two groups before and after the treatment.Results: After the treatment,the observation group’s uterine myoma size and uterine volume were significantly smaller than the control group(P<0.05);The observation group’s cure rate and total effective rate were significantly higher than the control group(P<0.05);E2 and P levels in the observation group after treatment were significantly lower than that of the control group(P<0.05);The adverse reactions in both of the two groups were relatively minor.Conclusion: For uterine fibroids,mifepristone combined with guizhifuling capsule has good efficacy and less adverse reactions.It can be used as a better conservative treatment option for the treatment of uterine fibroids.
Keywords:Uterine fibroids  Mifepristone  Guizhifuling capsule  Sex hormone level
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