女性生殖系统支原体培养与药物敏感性分析

目的:分析女性生殖系统支原体培养与药物敏感性.方法:取本院妇科于2007年4月~2011年4月收治的生殖系统感染患者864人为研究时象,使用无菌消毒棉球擦拭患者宫颈外周,将无茵拭子深入到患者宫颈内1~2cm.轻轻转动3～6圈后取出,放入与无菌拭子配套的无菌试管中,立即送检.结果:864名生殖系统感染患者中,支原体培养阳性503人,阳性率58.2%,其中解脲支原体(UU)感染318人,阳性率36.8%;人型支原体(MH)感染31人,阳性率3.6%;UU+MH混合感染154人,阳性率17.8%.支原体敏感的药物为交沙霉素、克拉霉素、美满霉素、强力霉素,支原体耐药的药物为林可霉素、壮观霉素.结论:应将支原体的培养与药物敏感性的检测当做治疗前常规检测项目,以指导临床用药,减少临床耐药茵的产生,提高治疗效果,缩短治疗时间.

Culturing and drug sensitivity of mycoplasma in female reproductive system

Objectives: To analyze the culturing and drug sensitivity of mycoplasma in female reproductive system.Method: We selected 864 patients with reproductive system infections as the study subjects who were treated in our hospital from April 2007 to April 2011.We used sterile cotton ball to clean their cervical periphery,put sterile swab 1-2 CM deep into patients’ cervix,turned gently for 3-6 circles,took the sterile swab out,put it into corresponding sterile tube,and sent it for check immediately.Result: Out of 864 reproductive system infection patients,503 were positive in mycoplasma culturing(positive rate: 58.2%),318 were infected with ureaplasma urealyticum(UU)(positive rate: 36.8%),31 were infected with mycoplasma hominis(MH)(positive rate: 3.6%) and 154 were infected with UU and MH(positive rate: 17.8%).Mycoplasma was sensitive to josamycin,clarithromycin,minocycline and doxycycline,and had drug resistance to lincomycin and spectinomycin.Conclusion: The culturing and drug sensitivity test of mycoplasma should be applied as the routine tests before treatment,so as to provide a guide for clinical medication,to reduce the occurrence of drug resistance,to improve the efficacy and to shorten the time of therapy.