88例女性继发性不孕病因分析

目的：探讨继发性不孕症患者发生的原因,为临床诊治提供研究依据。方法：回顾性分析2012年5月至2013年5月于本院就诊的88例继发性不孕症妇女（观察组）以及100例同期行妇科检查的健康妇女（对照组）的临床资料,对不孕症的原因进行分析。结果：观察组流产史、输卵管阻塞、子宫内膜病变、支原体感染、排卵障碍、盆腔粘连发生率显著高于对照组,差异有统计学意义（P〈0.05）。沙眼衣原体（CT）、解脲支原体（UU）以及人型支原体（MH）同时感染者不孕症发生率显著高于1种或2种支原体感染者,差异有统计学意义（P〈0.05）。支原体阳性组患者流产史、输卵管阻塞、子宫内膜病变、盆腔粘连发生率显著高于阴性组,差异有统计学意义（P〈0.05）。随着支原体感染种类的增加,患者流产史、输卵管阻塞、子宫内膜病变、盆腔粘连发生率显著增加。结论：引起继发性不孕症的因素众多,其中支原体感染是引起继发性不孕症的主要因素,对患者进行诊治时,应综合考虑各种因素,同时加强对支原体感染的预防,以降低继发性不孕症的发生率。

Etiological analysis of 88 cases of female secondary infertility

Objectives： To investigate the causes of secondary infertility to improve research basis for clinical diagnosis and treatment. Method： The clinical data of 88 patients with secondary infertility women（ observation group） having received treatment in our hospital between May 2012 and May 2013,and 100 cases of healthy women（ control group） received obstetric examination in our hospital at the same time was analyzed. Results： The occurrence rate of abortion,tubal obstruction,endometrial lesions,mycoplasma infection,ovulation disorders and pelvic adhesions of the observation group was significantly higher than those of the control group,which was statistically significant（ P〈0. 05）. The occurrence rate of infertility patients,who were infected by Chlamydia trachomatis（ CT）, Ureaplasma urealyticum（ UU） and Mycoplasma hominis（ MH） at the same time,was significantly higher than these who were infected by one or two kinds of mycoplasma. The difference was statistically significant（ P〈0. 05）. The occurrence rate of abortion,tubal obstruction,endometrial lesions,and pelvic adhesions in mycoplasma positive group was significantly higher than the negative group. The difference was statistically significant（ P〈0. 05）. With increases in species of mycoplasma infection,occurrence rate of abortion,tubal obstruction,endometrial lesions and pelvic adhesions increased significantly. Conclusion： There are many factors causing secondary infertility,among which mycoplasma infection is a major one. In the diagnosis and treatment,doctors should consider various factors and strengthen the prevention of mycoplasma infection in order to reduce the incidence of secondary infertility.