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1599例前列腺液标本支原体感染检测及药敏结果分析
引用本文:周兴,;何清湖,;周青,;朱惠斌.1599例前列腺液标本支原体感染检测及药敏结果分析[J].中国性科学,2014(12):9-11.
作者姓名:周兴  ;何清湖  ;周青  ;朱惠斌
作者单位:[1]湖南中医药大学第一附属医院男性病科,长沙410007; [2]湖南中医药大学,长沙410208; [3]湖南中医药大学第一附属医院检验科,长沙410007
基金项目:国家自然科学基金(81373641;81202706).
摘    要:目的:回顾本地区男性泌尿生殖道患者感染解脲支原体(UU)、人型支原体(MH)的分布状况,了解支原体对12种抗生素体外药物敏感试验的现状。方法:对1599例男性泌尿生殖道感染患者前列腺液标本进行支原体(Uu、MH)培养及药敏试验。结果:1599例检测标本中,总感染率为23.08%,单纯UU阳性277例(75.07%),UU -Mh 阳性81例(21.95%),单纯 Mh 阳性11例(2.98%)。MH 对强力霉素(DOX)、交沙霉素(JOS)、美满霉素(MIN)全部敏感,UU 对JOS、MIN、DOX、环酯红霉素(ECC)、克拉霉素(CLA)均非常敏感,UU-MH混合感染的耐药率明显高于单纯UU或MH感染。结论:临床治疗支原体感染时应尽量根据药敏结果选择敏感药物,DOX、MIN和JOS可作为本地区临床经验用药的首选药物。

关 键 词:男性  解脲支原体  人型支原体  药物敏感性实验

Detection of mycoplasma from prostatic fluid in 1599 patients and their antibiotic susceptibilities study
Institution:ZHOU Xing, HE Qinghu, ZHOU Qing, ZHU Huibin( 1. Andrology Department, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha 410007, China; 2. Hunan University of Chinese Medicine, Changsha 410208, China; 3. Clinical Laboratory, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha 410007, China)
Abstract:Objectives:To review the incidences of urogenital tract infection caused by ureaplasma urealyti-cum (UU)and mycoplasma hominis (MH)and their susceptibilities to 12 antibiotic agents.Methods:UU and MH were cultured and their drug susceptibilities from 1 ,599 patients with urogenital tract infections were statistically analyzed.Results:The overall positive incidence of gential mycoplasmas was 23.08%.The most common pattern was UU mono-infection (75.07%);the UU-MH co-infection pattern ranked second (21.95%)and MH mono-infection was lowest (2.98%).However,a significantly higher infection rate by genital mycoplasmas was found in young men (age range:21 -50 years).Overall,MH complete susceptibility to doxycycline (DOX),josamycin (JOS)and minocycline (MIN),while UU had high susceptibility rates to JOS,MIN,DOX,erythromycin cyclocar-bonate (ECC)and clarithromycin (CLA).The resistance rates of UU-MH-mixed isolates to most of drugs were significantly higher than those of UU-or MH-single isolates.Conclusions:The laboratory screening and antimi-crobial susceptibility testing for genital mycoplasmas is vital to treat the infection.According to the empirical treat-ment of mycoplasma infection,DOX,MIN,and JOS can be taken as the drugs of first choice.
Keywords:Men  Ureaplasma urealyticum (Uu)  Mycoplasma hominis (MH)  Drug susceptibili-ties
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