青春期后女性痤疮患者血清性激素水平的研究

目的：检测青春期后女性痤疮患者体内性激素的水平。方法：采用放射免疫法对25岁以上的34例女性痤疮患者血清睾酮（T）、雌二醇（E2）、泌尿素（PRL）、黄体生成素（LH）和卵泡刺激素（FSH）进行了测定，并以32例正常女性作为对照。结果：患者组T显著高于对照组（P＜0．001）；E2和LH显著低于对照组（P＜0．001）；PRL和FSH无明显变化（P＞0．05）。结论：性激素异常可能是女性痤疮迟发和持久不退的主要原因。

Study on serum sex hormone levels in women with postadolescent acne

Objective: To mearure the level of serum sex hormones in women with postadolescent acne. Methods: The seurm levels of testosterone (T), estradiol (E 2), prolactin (PRL) luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured with radioimmunoassay in 34 women with acne over the age of 25 years old, 32 healthy subjects were selected as control. Results: The result revealed that the level of T in patients were significantly higher than that in control subjects (P<0.001 ). The levels of E 2 and LH in patients were significantly lower (P<0.001 ) and the levels of PRL and FSH showed no significant differences between patients and control subjects (P>0.05 ). Conclusion : The study indicates that sex hormones abnormality may be the major factor related to the late onset or persistent acne in women.