| 依奇珠单抗治疗儿童脓疱型银屑病一例 |
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| 引用本文： | 陈祚玺,张园,赵晴,施仲香,孙勇虎,张福仁.依奇珠单抗治疗儿童脓疱型银屑病一例[J].中国麻风皮肤病杂志,2021,37(12):801-803. |
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| 作者姓名： | 陈祚玺 张园 赵晴 施仲香 孙勇虎 张福仁 |
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| 作者单位： | 1山东大学齐鲁医学院，山东济南，250012；
2山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，济南，250022 |
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| 摘 要： | 有文献报道脓疱型银屑病的发生和发展与IL-17A有关，使用IL-17A拮抗剂可一定程度上逆转银屑病的分子生物学过程，从而改善患者的临床症状。目前有依奇珠单抗治疗成年人脓疱型银屑病的报道，但尚未有其治疗儿童脓疱型银屑病的报道，本文报道依奇珠单抗成功治疗12岁脓疱型银屑病患儿一例。
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| 关 键 词： | 脓疱型银屑病 儿童 依奇珠单抗 |
Treatment of childhood pustular psoriasis with ixekizumab: a case report |
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| CHEN Zuoxi,ZHANG Yuan,ZHAO Qing,SHI Zhongxiang,SUN Yonghu,ZHANG Furen.Treatment of childhood pustular psoriasis with ixekizumab: a case report[J].China Journal of Leprosy and Skin Diseases,2021,37(12):801-803. |
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| Authors: | CHEN Zuoxi ZHANG Yuan ZHAO Qing SHI Zhongxiang SUN Yonghu ZHANG Furen |
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| Institution: | 1 Cheeloo College of Medicine, Shandong University, Jinan 250012, China;
2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China |
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| Abstract: | It has been reported that the occurrence and development of pustular psoriasis is related to IL-17A, and IL-17A antagonists can reverse the molecular biological process of psoriasis and improve the clinical symptoms of patients. Ixekizumab has been used to treat pustular psoriasis in adult, but there was no report of ixekizumab in the treatment of the child with pustular psoriasis. We report a case of 12-year-old girl with pustular psoriasis who responds well to ixekizumab treatment. |
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| Keywords: | pustular psoriasis childhood ixekizumab |
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