| 瘢痕疙瘩发病机制研究进展 |
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| 引用本文： | 马卉,张润田,曲天歌,包海兰,李玲玲,段行武.瘢痕疙瘩发病机制研究进展[J].中国麻风皮肤病杂志,2019,35(6):375-379. |
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| 作者姓名： | 马卉 张润田 曲天歌 包海兰 李玲玲 段行武 |
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| 作者单位： | 北京中医药大学东直门医院皮肤科，北京 100700 |
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| 基金项目： | 北京中医药大学、级自主课题-青年教师项目(编号:2016-JYB-JS-050);2017青苗人才培养计划(编号:DZMYS-201705);2016杰出青年人才项目(编号:2016-JYB-XJQ005);2016青苗人才培养计划(编号:DZMYS-201603) |
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| 摘 要： | 瘢痕疙瘩常超出原伤口界限,呈侵袭性生长、瘤样增生,伴痒痛不适,单纯手术切除后易复发,治愈十分困难。目前其机制研究涉及多基因、多细胞、多分子以及多通路,但仍未取得突破性进展。本文就瘢痕疙瘩发病机制进行综述,以期为科学研究及临床治疗提供更多思路。
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| 关 键 词： | 瘢痕疙瘩 发病机制 |
Progress in the pathogenesis of keloid |
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| MA hui,ZHANG Runtian,QU Tiange,BAO Hailan,LI Lingling,DUAN Xingwu.Progress in the pathogenesis of keloid[J].China Journal of Leprosy and Skin Diseases,2019,35(6):375-379. |
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| Authors: | MA hui ZHANG Runtian QU Tiange BAO Hailan LI Lingling DUAN Xingwu |
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| Institution: | Dongzhimen Hospital, Beijing University of Chinese Medcine，Beijing 100700, China |
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| Abstract: | The lesions of keloid often exceed the original wound boundaries, showing aggressive growth, tumor-like hyperplasia, accompanied by itching and pain. It's difficult to cure and often recur after simple surgical resection. Although studies on its mechanism involve polygenes, cells, molecules and pathways, no breakthrough has been made. The pathogenesis of keloid is reviewed in this paper in order to provide more ideas for scientific research and clinical treatment. |
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| Keywords: | keloid pathogenesis |
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