| 次抑菌浓度的药物诱导解脲支原体人型支原体耐药与交叉耐药的研究 |
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| 引用本文： | 朱翠明,吴移谋,余敏君,尹卫国.次抑菌浓度的药物诱导解脲支原体人型支原体耐药与交叉耐药的研究[J].中国皮肤性病学杂志,2000,14(2):86-87. |
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| 作者姓名： | 朱翠明 吴移谋 余敏君 尹卫国 |
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| 作者单位： | 衡阳医学院微生物学教研室,421001 |
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| 基金项目： | 湖南省科委资助重点课题部分工作 |
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| 摘 要： | 目的 为了解ＵＵ和ＭＨ的耐药状况，指导临床合理用药。方法 将临床标本分离的６株ＵＵ与６株ＭＨ分别进行了诱导与交叉耐药试验。结果 ＴＣ诱导耐药的ＵＵ和ＭＨ亦对ＤＯＸＹ耐药，但对ＭＣ，喹诺酮类药物和大环内酯类药物无明显交叉耐约性。ＯＦＬＸ诱导耐药的ＵＵ和ＭＨ和ＣＦＬ，Ｘ，ＬＭＬＸ耐药人型支原体耐药与交叉耐药的地四环素类药物和大环内酯类药物没有显著的交叉耐药性。结论 耐ＴＣ的ＵＵ与ＭＨ株对ＤＯＸＹ呈现交
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| 关 键 词： | 解脲支原体 人型支原体 耐药 交叉耐药 抗生素 |
| 修稿时间： | 1998年11月18 |
Inducing Urogenital Mycoplasmas Resistance and Cross-resistance with Antibiotic Subinhibitory Concentration. |
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| Zhu Cuiming,Wu Yimou,Yu Minjun,et al..Inducing Urogenital Mycoplasmas Resistance and Cross-resistance with Antibiotic Subinhibitory Concentration.[J].The Chinese Journal of Dermatovenereology,2000,14(2):86-87. |
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| Authors: | Zhu Cuiming Wu Yimou Yu Minjun |
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| Institution: | Zhu Cuiming,Wu Yimou,Yu Minjun,et al.Department of Microbiology,Hengyang Medical College,Hengyang 421001 |
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| Abstract: | Objective To acquire the information about the present resistance characteristics in Ureaplasma urealyticum(UU) and Mycoplasma hominis(Mh),and to instruct reasonable application of antibiotice clinically.Methods A total of 6 isolates of UU and Mh was collected from infectious urogenital samples.lnducted and cross resistance were tested. Results Tetracyclineresistant UU and Mh showed resistance to doxycycline,but none of species showed cross resistance to minocycline and quinolones and macrolides.Ofloxacin resistant UU and Mh showed resistance to ciprofloxacin and lomefloxacin,but none of species showed cross resistance to tetracycline and macrolides.Conclusion Tetracycline resistant UU and MH have cross resistance to doxycycline,ofloxacin resistance UU and MH have cross resistance to ciprofloxacin and lomefloxacin. |
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| Keywords: | UU MH Resistance Cross resistance |
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