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阴性精神分裂症患者局部脑血流与威斯康星卡片分类测验的相关分析
引用本文:刘哲宁,杨玲玲,苏见知,解亚宁,赵靖平,许明智,尹翼,吴永刚.阴性精神分裂症患者局部脑血流与威斯康星卡片分类测验的相关分析[J].中国临床心理学杂志,1997(2).
作者姓名:刘哲宁  杨玲玲  苏见知  解亚宁  赵靖平  许明智  尹翼  吴永刚
作者单位:湖南医科大学附二医院
摘    要:目的:为探讨阴性精神分裂症患者脑结构与认知功能缺陷的关系。方法:运用单光子发射计算机断层扫描(SPECT),测定了12例阴性精神分裂症患者在安静状态与威斯康星卡片分类测验的负荷状态下的局部脑血流。结果:在安静状态下阴性精神分裂症病人的脑局部放射性分布是对称的,但在威斯康星卡片分类测验的刺激状态下左、右侧额叶的局部脑放射性计数是不对称的。结论:提示精神分裂症的阴性症状与左侧额叶的功能状态有关。

关 键 词:精神分裂症  局部脑血流  抽象思维

Relationship Between Regional Cerebral Blood Flow and Wisconsin Card Sorting Test in Negative Schizophrenia
Liu Zhening,Yang Lingling,Su Jianzhi et al Second Affiliated Hospital,Hunan Medical University,Changsha.Relationship Between Regional Cerebral Blood Flow and Wisconsin Card Sorting Test in Negative Schizophrenia[J].Chinese Journal of Clinical Psychology,1997(2).
Authors:Liu Zhening  Yang Lingling  Su Jianzhi Second Affiliated Hospital  Hunan Medical University  Changsha
Abstract:Objective: To explore the relationship between regional cerebral blood flow (rCBF) andexecutive functions in negative schizophrenia.Method: 12 negative schizophrenic patients were studied with single photon emission computer tomography(SPECT). Measures of rCBF were taken at rest and during a frontal activation task using the Wisconsin Card Sorting Test (WCST).Results:Reliable inter-hermispheric differences in the frontal region were observed among patients during testing of WCST but not during rest condition. Significant correlation was also found between left frontal rCBF and the number of perseverative errors in WCST.Conclusion:These results suggest that negative symptoms of schizophrenia might be related to left frontal executive functions.
Keywords:Schizophrenia  Regional cerebral blood flow  Executive functions  
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