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氟哌啶醇与利培酮对精神分裂症患者生活质量的影响
引用本文:任清涛,闫加民,李广.氟哌啶醇与利培酮对精神分裂症患者生活质量的影响[J].中国临床心理学杂志,2002,10(2):150-151.
作者姓名:任清涛  闫加民  李广
作者单位:1. 山东淄博市精神病医院,山东,淄博,255120
2. 山东淄博万杰医院
3. 山东淄博卫生学校
摘    要:精神分裂症是一种慢性疾病 ,需长期服药治疗 ,而抗精神病药物在治疗的同时 ,又可出现毒副作用 ,对患者的生活质量产生不利影响。本文就氟哌啶醇与利培酮作一比较研究 ,报道于后。1 对象与方法1.1 研究对象病例选自连续来我院就诊的门诊患者。入组标准 :①患者符合CCMD -Ⅱ -R精神分裂症诊断标准1] ,②阳性与阴性症状量表 (PANSS)总分≥ 6 0分 ,③年龄在 180~ 5 0岁 ,④病程 3个月~ 2年 ,⑤未经系统治疗 ,⑥无严重躯体疾病。按标准共收集 130名精神分裂症患者 ,随机分为甲、乙两组 ,甲组为氟哌啶醇组 6 4例 ;乙组为利培酮组 6…

关 键 词:氟哌啶醇  利培酮  精神分裂症  生活质量  影响
文章编号:1005-3611(2002)02-0150-02
修稿时间:2001年3月6日

Effect of Haloperidol and Risperidone on the Life Quality of the Patients with Schizophrenia
REN Qing-tao,YAN jia-min,LI Guang Mental Hospital of Zibo,Zibo ,China.Effect of Haloperidol and Risperidone on the Life Quality of the Patients with Schizophrenia[J].Chinese Journal of Clinical Psychology,2002,10(2):150-151.
Authors:REN Qing-tao  YAN jia-min  LI Guang Mental Hospital of Zibo  Zibo  China
Institution:REN Qing-tao,YAN jia-min,LI Guang Mental Hospital of Zibo,Zibo 255120,China
Abstract:Objective: To compare the effects between haloperidol and rieperidone on quality of life in patients with schizophrenia. Methods: The patients with schizophrenia treated respectively by haloperidol and risperidone were compared by double blind method. The General Quality of Life Inventory (GQOLI) was used to evaluate the life quality, while the Positive and Negative Symptoms Scale (PANSS) and the Treatment Emergent Symptom Scale (TESS) were used to assess the efficacy and side effects. Results: The risperidone group showed better effects than the haloperidol group in the domains of physical function ,mental health and social function The difference was significant (P<0.01). Conclusion: The quality of life of Schizophrenic patients treated by haloperidol were poorer than that of risperidone.
Keywords:Schizophrenia  Haloperidol  Risperidone  Quality of life
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