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帕金森病患者的交感神经皮肤反应研究
引用本文:张宁,穆俊林,王夏红,宋景贵,顾仁骏.帕金森病患者的交感神经皮肤反应研究[J].临床神经电生理学杂志,2006,15(3):161-163.
作者姓名:张宁  穆俊林  王夏红  宋景贵  顾仁骏
作者单位:453002,河南新乡,河南省精神病医院,新乡医学院第二附属医院诱发电位室
摘    要:目的:研究帕金森病(PD)患者的自主神经功能情况。方法:对40例PD患者和38例健康者分别进行了交感神经皮肤反应(SSR)测定,并将结果加以比较。结果:PD组SSR测定异常率为 75%(30/40),SSR波潜伏期明显延长,波幅降低,与对照组相比差异有显著意义(P<0.01)。结论:PD 患者存在一定的自主神经功能损害,SSR可作为判断PD患者的自主神经功能的参考指标。

关 键 词:帕金森病(PD)  自主神经功能  交感神经皮肤反应(SSR)
文章编号:1009-5934(2006)-03-161-03
收稿时间:2005-08-08
修稿时间:2005-12-15

A study on sympathetic skin response in patients with Parkinson disease
ZHANG Ling,MU Junlin, WANG Xiahong,et al , China.A study on sympathetic skin response in patients with Parkinson disease[J].Journal of Clinical Electroneurophysiology,2006,15(3):161-163.
Authors:ZHANG Ling  MU Junlin  WANG Xiahong    China
Abstract:Objective:To explore the autonomic nerve dysfunction in patients with Parkinson disease (PD),in order to find the diagnostic index with these patients. Method:Sympathetic skin response (SSR) tests were performed for 40 PD patients and 38 healthy people. The results were compared between two groups. Result:The abnormality rate of SSR in PD patients was 75% (30/40) ,the latency of SSR was longer and the amplitude of SSR was lower in PD patients than in the control group. There was significant difference between the two groups(P<0.01). Conclusion:The PD patients have autonomic nerve dysfunction. SSR test can be used as an index to appraise the autonomic nerve function of PD patients in clinical diagnosis and treatment.
Keywords:Parkinson disease(PD)  Autonomic nerve function  Sympathetic skin response(SSR)
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