| 奎硫平对精神分裂症患者的疗效及其生活质量的影响 |
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| 引用本文： | 郭振宇,刘家梅,杨建章,郭华,王爱勤.奎硫平对精神分裂症患者的疗效及其生活质量的影响[J].中国健康心理学杂志,2008,16(5):544-546. |
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| 作者姓名： | 郭振宇 刘家梅 杨建章 郭华 王爱勤 |
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| 作者单位： | 中国.河南省驻马店市精神病医院,463000 |
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| 摘 要： | 目的比较奎硫平与氯丙嗪治疗精神分裂症患者的疗效及对生活质量的影响。方法把入组对象随机分为研究组和对照组,以阴性与阳性症状量表(PANSS)评定疗效,以副反应量表(TESS)评定副反应,以世界卫生组织生活质量问卷(WHO-QOT-100)评定生活质量,观察16周。结果两组PANSS评分2周时统计学分析差异显著(P<0.05),至16周时仍存在显著差异(P<0.01);对阴性症状治疗8周时,两组比较差异显著(P<0.01),16周这种差异很显著(P<0.01);两组TESS评分治疗后2、4、8、16周均为显著差异(P均<0.01);两组的WHOQOT-100评分除环境维度外,其余维度评分与对照组相比均有显著差异(P<0.05或P<0.01)。结论奎硫平与氯丙嗪相比能较好、较快改善精神症状,较好地提高病人的生活质量。
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| 关 键 词： | 奎硫平 氯丙嗪 精神分裂症 生活质量 |
| 修稿时间： | 2007年10月30 |
Efficacy Quetiapine in the Treatment of Schizophrenic Patients and Effect on the Quality of Life |
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| Guo Zhenyu,Liu Jiamei,Yang Jianzhang,et al..Efficacy Quetiapine in the Treatment of Schizophrenic Patients and Effect on the Quality of Life[J].china journal of health psychology,2008,16(5):544-546. |
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| Authors: | Guo Zhenyu Liu Jiamei Yang Jianzhang |
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| Institution: | Guo Zhenyu,Liu Jiamei,Yang Jianzhang,et al.Zhumadian Mental Hospital,Zhumadian 463000,P.R.China |
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| Abstract: | Objective To compare the efficacy and the quality of life of schizophrenic patients treated with quetiapine and Chlorpromazine.Mehtods The schizophrenic patients were randomly divided into quetiapine group and Chlorpromazine group.Treated for 16 weeks,the efficacy was measured with the positive and negative symptoms scale(PNSS),the side effects was assessed with TESS,while the quality of life was assessed with WHO QOL-100.Results There was significant difference between the score of PANSS in two groups afte... |
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| Keywords: | Quetiapine Chlorpromazine Schizophrenia Quality of life |
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