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齐拉西酮与利培酮治疗首发精神分裂症对照研究
引用本文:刘璐,王新法,张志勇.齐拉西酮与利培酮治疗首发精神分裂症对照研究[J].中国健康心理学杂志,2009,17(4):458-459.
作者姓名:刘璐  王新法  张志勇
作者单位:中国.河南省精神病医院(新乡),453002
摘    要:目的评价齐拉西酮治疗首发精神分裂症的疗效和安全性。方法对76例首发精神分裂症患者分别使用齐拉西酮与利培酮治疗8周,采用阳性与阴性症状量表(PANSS)、临床疗效总评量表的病情严重程度(CGI-SI)、副反应量表(TESS)评定疗效和安全性。结果治疗2、4、8周末两组PANSS总分及各因子分与疗前比较差异有显著性(P〈0.01)。两组间比较各周PANSS总分及各因子分差异无显著性(P〉0.05),TESS评分差异无显著性(P〉0.05)。结论齐拉西酮治疗首发精神分裂症的疗效和安全性与利培酮相当。

关 键 词:精神分裂症  齐拉西酮  利培酮  副反应量表

Control Study of Ziprasidone and Risperidone in the Treatmnet of First-episode Schizophrenia
Liu Lu,Wang Xinfa,Zhang Zhiyong.Control Study of Ziprasidone and Risperidone in the Treatmnet of First-episode Schizophrenia[J].china journal of health psychology,2009,17(4):458-459.
Authors:Liu Lu  Wang Xinfa  Zhang Zhiyong
Institution:Liu Lu,Wang Xinfa,Zhang Zhiyong.Department of Psychiatry,The Second Affiliated Hospital of Xinxiang Medical College,Henan 453002,P.R.China
Abstract:Objective To study the efficacy and safety of Ziprasidone in the treatment of first-episode schizophrenia.Methods 76 cases of first-episode schizophrenics were randomly enrolled into two groups and were treated with Ziprasidone and Risperidone respectively.The duration of study was 8 weeks.The PANSS, CGI-SI and TESS were employed for assessing the therapeutic efficacy and safety respectively.Results After treatment,the total scores of PANSS and all the factors' scores were significantly different comparing ...
Keywords:Schizophrenia  Ziprasidone  Risperidone  TESS  
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