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Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
Institution:1. Center for Cell Clearance, University of Virginia, Charlottesville, VA 22908, USA;2. Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA;3. Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA;4. Carter Immunology Center, University of Virginia, Charlottesville, VA 22908, USA;5. Institute of Biotechnology and Department of Medical Science, National Tsing Hua University, Hsinchu, 30071, Taiwan;6. Department of Biochemistry and Genetics, La Trobe University, Melbourne, VIC 3083, Australia;7. VIB/UGent Inflammation Research Centre and the Department of Biomedical Molecular Biology, Ghent University, 9000 Ghent, Belgium
Abstract:
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  • Keywords:Pannexin 1  extracellular ATP  lung  asthma  airway inflammation  T regulatory cell  T effector cell  Salt-inducible kinase  CD4 T cell  adenosine
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