| 急性高碳酸血症对膈肌功能的影响 |
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| 引用本文： | 佟万成,王东林.急性高碳酸血症对膈肌功能的影响[J].基础医学与临床,1997,17(2):139-141. |
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| 作者姓名： | 佟万成 王东林 |
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| 作者单位： | 中国医学科学院，中国协和医科大学，北京协和医院呼吸科，第三军医大学新桥医院呼吸科 |
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| 摘 要： | 本文用电刺激犬膈神经（ＰＮＳ）、记录经膈压（Ｐｄｉ）－刺激频率（Ｆ）曲线、分析自主呼吸膈肌肌电频谱（ＥＭＧｄｉ）的方法，研究急性ＣＯ２潴留对膈肌功能的影响，并探讨ｐＨ值在其中的作用。发现：１．急性ＣＯ２潴留使Ｐｄｉ进行性下降、Ｐｄｉ－Ｆ曲线右移，ＥＭＧｄｉ频谱改变；２．维持正常的ｐＨ值可减轻Ｐｄｉ、ＥＭＧｄｉ的改变。提示急性ＣＯ２潴留严重损害膈肌功能，ｐＨ的变化于其中起重要作用。
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| 关 键 词： | 呼吸肌疲劳，经膈压，膈肌肌电图，CO_2潴留 |
The Effect of Acute Hypercapnia on Diaphragmatic Function |
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| Tong Wancheng Wang Donglin,Guo Xianjian.The Effect of Acute Hypercapnia on Diaphragmatic Function[J].Basic Medical Sciences and Clinics,1997,17(2):139-141. |
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| Authors: | Tong Wancheng Wang Donglin Guo Xianjian |
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| Abstract: | he effect of acute hypercapnia ( AH ) on diaphragmatic function was investigated on openchest , machanically vetilated dogs. The diaphragmatic function was assessed by measuringtransdiaphragmatic pressure ( Pdi ) -stimulating frequency ( F ) curve during phrenic nerve stimulating and analysis the power spetrum of diaphragmatic electromygram ( EMGdi ) in spontanously breathing. It was found that Pdi decreased , Pdi-F curve shifted to the right andEMGdi changed markedly afrer AH but slightly with AH and normal pH. It was concluded thatAH damaged diaphragmatic function mainly through the acute change of pH. |
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| Keywords: | respiratory muscle fatigue transdiaphragmatic pressure electromygram hypercapnia Department of Respiratory Disease Xinqiao Hospital The Theird Military Medical College |
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