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Anti-inflammatory Effects of Novel P2X4 Receptor Antagonists,NC-2600 and NP-1815-PX,in a Murine Model of Colitis |
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| Authors: | D’Antongiovanni Vanessa Pellegrini Carolina Benvenuti Laura Fornai Matteo Di Salvo Clelia Natale Gianfranco Ryskalin Larisa Bertani Lorenzo Lucarini Elena Di Cesare Mannelli Lorenzo Ghelardini Carla Nemeth Zoltan H Haskó György Antonioli Luca |
| Institution: | 1.Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy ;2.Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy ;3.Department of Neuroscience, Psychology, Drug Research and Child Health, Neurofarba, Pharmacology and Toxicology Section, University of Florence, Florence, Italy ;4.Department of Surgery, Morristown Medical Center, Morristown, NJ, 07960, USA ;5.Department of Anesthesiology, Columbia University Irving Medical Center, New York, NY, 10032, USA ;6.Unit of Pharmacology and Pharmacovigilance, Department of Clinical and Experimental Medicine, University of Pisa Via Roma 55, 56126 Pisa, Italy ; |
| Abstract: | Inflammation - The pharmacological blockade of P2X4 receptors has shown potential benefits in the management of several immune/inflammatory diseases. However, data regarding the involvement of P2X4... |
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