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T-Synthase活性对胃癌Tn/STn及T/ST抗原表达的影响
引用本文:胡涛,刘希伟,付强,董孟华,张海霞,张骞.T-Synthase活性对胃癌Tn/STn及T/ST抗原表达的影响[J].中华微生物学和免疫学杂志,2009,29(8).
作者姓名:胡涛  刘希伟  付强  董孟华  张海霞  张骞
作者单位:1. 滨州医学院免疫学教研室,烟台,264003
2. 滨州医学院解剖学教研室,烟台,264003
摘    要:胞;Tn+细胞同时表达Tn/STn抗原,不表达T/ST抗原,Tn-Ⅰ及Tn-细胞均表达ST抗原,部分Tn-Ⅰ细胞可见T抗原表达;Tn+、Tn-Ⅰ及Tn-细胞间T-Synthase mRNA无明显差别,T-Synthase活性在Tn+细胞明显下降.结论 不同TNM期胃癌组织中Tn、STn、T、ST抗原表达存在差异,T-Synthase活性降低可能导致胃癌细胞表达Tn抗原.

关 键 词:胃癌  Tn抗原  T抗原

Effects of T-Synthase activity on the expressing of Tn/STn and T/ST antigens in gastric carcinoma tissues
HU Tao,LIU Xi-wei,FU Qiang,DONG Meng-hua,ZHANG Hai-xia,ZHANG Qian.Effects of T-Synthase activity on the expressing of Tn/STn and T/ST antigens in gastric carcinoma tissues[J].Chinese Journal of Microbiology and Immunology,2009,29(8).
Authors:HU Tao  LIU Xi-wei  FU Qiang  DONG Meng-hua  ZHANG Hai-xia  ZHANG Qian
Abstract:acts was much lower than that in Tn-cell.Conclusion The expression of Tn,STn,T and ST antigen in gastric carcinoma tissues of different TNM stages is different.Tn antigen expression in tumor cells may be caused by the decrease of T-Synthase activity.
Keywords:T-Synthase
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