冠心病危险因素聚集与冠状动脉狭窄的关系研究

目的探讨冠心病危险因素聚集对冠状动脉狭窄的影响。方法以选择性冠状动脉造影为金标准,对2993例临床诊断冠心病患者的冠心病危险因素(高龄、男性、糖尿病、高脂血症、高血压以及吸烟)进行调查。结果随着伴发危险因素数目的增加,冠脉造影阳性率随着伴发危险因素数目的增加而明显上升,冠脉多支病变比例显著增加,重度和闭塞病变所占比例呈上升趋势。结论冠状动脉病变水平与伴随冠心病危险因素数量有关,危险因素越多,冠心病发生机率越高,累及支数越广,狭窄程度越重。

Relationship Between Risk Factors of Coronary Heart Disease and the Severity of Coronary Artery Lesions

Objective To investigate the relationship between the clustering of coronary heart disease(CHD) risk factors and the severity of coronary artery lesions. Methods A total of 2993 consecutive patients suspected of CHD were studied respectively. All patients underwent selective coronary angiography and received a survey of risk factors, including advanced age, male, diabetes, hyperlipemia,hypertension and smoking. Results The clustering of the CHD risk factors was associated with positive rate of coronary angiography and the extent and the severity of coronary artery lesions. Conclusion Not only the development but also the severity of coronary artery lesions is affected by the clustering of the CHD risk factors.