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主动脉内囊反搏和天麻注射液联合使用对山羊心肌缺血──再灌注损伤的改善作用
引用本文:罗红琳,肖静,刘强,王正荣,李时锋,张丽蓉,薛振南.主动脉内囊反搏和天麻注射液联合使用对山羊心肌缺血──再灌注损伤的改善作用[J].生物医学工程学杂志,1997(3).
作者姓名:罗红琳  肖静  刘强  王正荣  李时锋  张丽蓉  薛振南
作者单位:华西医科大学生物医学工程研究室!成都,610041,华西医科大学生物医学工程研究室!成都,610041,华西医科大学生物医学工程研究室!成都,610041,华西医科大学生物医学工程研究室!成都,610041,华西医科大学生物医学工程研究室!成都,610041,华西医科大学生物医学工程研究室!成都,6100
摘    要:采用结扎2h继而开放山羊冠状动脉分支方法,复制心肌缺血──再灌注模型,观察主动脉内囊反搏和天麻注射液联合使用对心肌坏死区面积的影响。所得结果与二者单独使用的结果进行了比较,发现主动脉内囊反搏和天麻注射液联合使用对限制心肌坏死区大小具有明显的协同作用。

关 键 词:主动脉内囊反搏  天麻注射液心肌缺血-再灌注  山羊

The Effect of Combining Intra-Aortic Balloon Pumping with Tianma Injection on Myocardial Ischemic-Reperfusional Injury in Goats
Luo Honglin, Xiao Jing, Liu Qiang, Wang Zhengrong,Li Shifeng, Zhang Lirong, Xue Zhengnan.The Effect of Combining Intra-Aortic Balloon Pumping with Tianma Injection on Myocardial Ischemic-Reperfusional Injury in Goats[J].Journal of Biomedical Engineering,1997(3).
Authors:Luo Honglin  Xiao Jing  Liu Qiang  Wang Zhengrong  Li Shifeng  Zhang Lirong  Xue Zhengnan
Abstract:The objective of this study was to explore the effect of combined Intra-Aortic Balloon Pumping (IABP) and Tianma injection on necrotic area in goat myocardial ischemic-reperfusional models which were established by two hours ischemia and a follow-up reperfusion. The results showed that the combined effect of IABPand Tianma Injection was more significant than that of IABP or Tianma separately. It is suggested that IABP andTianma injection have synergetic effect on the limitation of necrotic area, which possibly results from their mechanisms for decreasing the size of infarct.
Keywords:IABP Tianma injection Myocardial ischemia-reperfusion Goat
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