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不同设计心血管支架的血流动力学分析
引用本文:梁栋科,杨大智.不同设计心血管支架的血流动力学分析[J].生物医学工程学杂志,2006,23(6):1241-1244.
作者姓名:梁栋科  杨大智
作者单位:大连理工大学,材料科学与工程学院,大连,116023
基金项目:国家高技术研究发展计划(863计划)
摘    要:血液对血管壁的剪应力在支架内膜增生过程中起着非常重要的作用,低剪应力往往能促进内膜增生。我们利用计算流体动力学的方法,分析了定常流与脉动流两种条件下,支架植入引起的血管壁面剪应力的变化。结果发现:支架尺寸与结构的变化能够引起血管壁面剪应力的明显变化,这对于心血管支架的设计具有一定的指导意义。

关 键 词:剪应力  支架  内膜增生  计算流体动力学
收稿时间:2003-12-31
修稿时间:2003-12-312004-11-09

Hemodynamics Analysis of Intravascular Stents with Different Design Features
Liang Dongke,Yang Dazhi.Hemodynamics Analysis of Intravascular Stents with Different Design Features[J].Journal of Biomedical Engineering,2006,23(6):1241-1244.
Authors:Liang Dongke  Yang Dazhi
Institution:School of Material Science and Engineering, Dalian University of Technology, Dalian 116023,China
Abstract:Wall shear stress plays an important role in the development of in-stent restenosis. It has been demonstrated that low wall shear stress is associated with neointimal hyperplasia. We used computational fluid dynamics(CFD) to investigate the steady and pulsatile flows in the vicinity of model stents and focused on the changes of wall shear stress caused by the implanted stents. The results showed that wall shear stress depended greatly on the size and structure of the stents, which would have implications for the optimization of intravascular stent designs.
Keywords:Wall shear stress Stent Neointimal hyperplasia Computational fluid dynamics(CFD)
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