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| 妇女骨质疏松过程及运动防治模拟 | |
| 引用本文： | 马宗民,李淑娴,朱兴华,宫赫.妇女骨质疏松过程及运动防治模拟[J].生物医学工程学杂志,2007,24(1):124-128. |
| 作者姓名： | 马宗民 李淑娴 朱兴华 宫赫 |
| 作者单位： | 1. 大连大学,生物医学工程研究所,大连,116021 2. 大连大学,院士创业院,大连,116622 3. 吉林大学,工程力学系,长春,130025 |
| 基金项目： | 国家自然科学基金;高等学校博士学科点专项科研项目;大连大学校科研和教改项目 |
| 摘 要： | 应用带有力学调控系统的各向异性骨再造模型结合有限元法,进行妇女骨质疏松过程及运动防治的模拟。研究结果表明:在骨量下降初始阶段,下降平缓,绝经后骨量丢失加速,60岁时,骨量下降25.84%~28.63%,80岁时,骨量下降38.50%~40.44%,运动使外荷提高10%~20%后,可使骨量增加3.05%~10.26%,上述结果与临床观察结果基本一致。证明了肌力下降是妇女骨质疏松的主要因素,绝经则加快了妇女骨质疏松的过程。运动可减缓骨质疏松。 |
| 关 键 词： | 生物力学 骨质疏松 绝经 骨再造 模拟 |
| 修稿时间： | 2004-07-162005-04-04 |
Simulation on the Process of Female Osteoporosis and Its Prevention by Physical Activity |
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| Ma Zongmin,Li Shuxian,Zhu Xinghua,Gong He.Simulation on the Process of Female Osteoporosis and Its Prevention by Physical Activity[J].Journal of Biomedical Engineering,2007,24(1):124-128. | |
| Authors: | Ma Zongmin Li Shuxian Zhu Xinghua Gong He |
| Institution: | 1 Institute of Biomedical Engineering, Dalian University,Dalian 116021,China; 2 Academician Innovation Park, Dalian University,Dalian 116622,China; 3 Department of Engineering Mechanics, Jilin University, Changchun 130025,China |
| Abstract: | The processs of female Osteoporosis and its prevention by Physical activity were simulated using anisotropic bone remodelling model with mechanostat combining with finite element method.The results show that bone mass declines slowly at the beginning,bone loss accelerates in postmenopause and bone mass declines 25.84%-28.63% at the age of 60 and 38.50%-40.44% at the age of 80.Bone mass increases 3.05%-10.26% by an increase of 10%-20% in physical activity.The above results are consistent with clinical observations,which proves that declination of mechanical usage is the primary factor leading to osteoporosis,menopause quickens the process of female osteoporosis,physical activity can decelerate it. |
| Keywords: | Biomechanics Osteoporosis Menopause Bone remodeling Simulation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |