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Cell Area and Strut Distribution Changes of Bent Coronary Stents: A Finite Element Analysis
作者单位:ZHAO Yang,WU Wei(Department of Materials Engineering, Dalian University of Technology, Dalian 116024, China);YANG Da-zhi,QI Min(Department of Materials Engineering, Dalian University of Technology, Dalian 116024, China;State Key Laboratory of Materials Modification by Laser, Ion and Electron Beams, Dalian University of Technology,Dalian 116024, China)  
摘    要:Coronary stents are metal coils or mesh tubes delivered to blocked vessels through catheters, whic Recently, special drugs h are expanded by balloons to reopen and scaffold target vessels. are carried by stents (drug-eluting stents) to further reduce instent restenosis rate after stenting procedure. However, continual study on biomechanical characteristics of stents is necessary provide a more suitable drug loading for better interactions between stents and tissue, or to platform for drug-eluting stents. The purpose of this paper is to show how finite element methods can be used to study cell area and strut distribution changes of bent coronary stents. A same bending deformation was applied to two commercial coronary stent models by a rigid curved vessel. Results show that the stent design influenced the changes of cell area and strut distribution under bending situation. The stent with links had more cell area changes at outer curvature, and the stent with peak-peak ( 〉 〈 ) strut design could have strut contact and overlapping at inner curvature. In conclusion, this finite element method can be used to study and compare cell area and strut distribution changes of bent stents, and to provide a convenient tool for designers in testing and improving biomechanical characteristics of new stents.

关 键 词:冠状动脉支架  细胞面积  有限元分析  药物涂层支架  生物力学特性  冠状动脉内支架  弯曲变形  有限元方法

Cell Area and Strut Distribution Changes of Bent Coronary Stents: A Finite Element Analysis
Authors:ZHAO Yang  WU Wei  YANG Da-zhi  QI Min
Institution:1. Department of Materials Engineering, Dalian University of Technology, Dalian 116024, China
2. Department of Materials Engineering, Dalian University of Technology, Dalian 116024, China;State Key Laboratory of Materials Modification by Laser, Ion and Electron Beams, Dalian University of Technology,Dalian 116024, China
Abstract:Coronary stents are metal coils or mesh tubes delivered to blocked vessels through catheters, which are expanded by balloons to reopen and scaffold target vessels. Recently,special drugs are carried by stents (drug-eluting stents) to further reduce in-stent restenosis rate after stenting procedure. However,continual study on biomechanical characteristics of stents is necessary for better interactions between stents and tissue, or to provide a more suitable drug loading platform for drug-eluting stents. The purpose of this paper is to show how finite element methods can be used to study cell area and strut distribution changes of bent coronary stents. A same bending deformation was applied to two commercial coronary stent models by a rigid curved vessel. Results show that the stent design influenced the changes of cell area and strut distribution under bending situation. The stent with links had more cell area changes at outer curvature, and the stent with peak-peak (><) strut design could have strut contact and overlapping at inner curvature. In conclusion, this finite element method can be used to study and compare cell area and strut distribution changes of bent stents,and to provide a convenient tool for designers in testing and improving biomechanical characteristics of new stents.
Keywords:coronary stents  biomechanical characteristics  cell area  tissue prolapse  strut distribution  finite element methods
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