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Hemodynamics Simulation of Stenosed Coronary Bypass Graft
作者姓名:LIUYou-jun  QIAOAike  DUJian-jun
作者单位:[1]BiomechanicalLaboratory,BeijingPolytechnicUniversity,BeijinglO0022,China [2]不详,BeijingPolytechnicUniversity,BeijinglO0022,China
摘    要:By means of FEM, the physiological blood flow in coronary bypass graft is simulated. The stenosis in coronary artery is involved in the graft model,and the deformation of graft end to allow the surgical suture with a smaller diameter coronary is taken into consideration. The flow pattern, secondary flow and wall shear stress in the vicinity of anastomosis are analyzed. It is shown that a zone of low wall stress and high wall stress gradient exists downstream the toe. The floor opposed to the anastomosis is an area of high wall stress and high wall stress gradient. Both the toe downstream and the anastomosis bottom floor are prone to intimal hyperplasia.

关 键 词:血液动力学  动脉狭窄  冠状动脉  旁路血管移植

Hemodynamics Simulation of Stenosed Coronary Bypass Graft
LIUYou-jun QIAOAike DUJian-jun.Hemodynamics Simulation of Stenosed Coronary Bypass Graft[J].Chinese Journal of Biomedical Engineering,2005,14(1):7-16.
Authors:LIU You-jun  QIAO Aike  DU Jian-jun
Institution:Biomechanical Laboratory,Beijing Polytechnic University,Beijing 100022,China
Abstract:By means of FEM, the physiologi cal blood flow in coronary bypass graft is simula ted. The stenosis in coronary artery is involved in the graft model, and the def ormation of graft end to allow the surgical suture with a smaller diameter coron ary is taken into consideration. The flow pattern, secondary flow and wall shear stress in the vicinity of anastomosis are analyzed. It is shown that a zone of low wall stress and high wall stress gradient exists downstream the toe. The flo or opposed to the anastomosis is an area of high wall stress and high wall stres s gradient. Both the toe downstream and the anastomosis bottom floor are prone t o intimal hyperplasia.
Keywords:Hemodynamics  Numerical simulation  Coronary bypass  Wall shear stress
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