| 急性脑梗死患者血浆ET、CGRP的测定及其意义 |
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| 引用本文： | 奚宝珊,林兰,吴育彬. 急性脑梗死患者血浆ET、CGRP的测定及其意义[J]. 放射免疫学杂志, 2006, 19(3): 173-175 |
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| 作者姓名： | 奚宝珊 林兰 吴育彬 |
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| 作者单位： | 1. 汕头大学医学院第一附属医院核医学科,515041
2. 汕头大学医学院第一附属医院神经内科,515041 |
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| 基金项目： | 本文受广东省中医药局科研基金资助项目（1040100） |
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| 摘 要： | 目的：观察急性脑梗死患者血浆内皮素（endothelin，ET）、降钙素基因相关肽（CGRP）的临床意义。方法：检测42例急性脑梗死患者急性期与恢复期的ET与CGRP的水平，并与对照组进行比较分析。结果：检测结果发现急性期脑梗死者血浆内皮素高于对照组，而降钙素基因相关肽低于对照组；急性期与恢复期比较，内皮素与降钙素基因相关肽均有显著差异（P〈0．01或P〈0．05）。结论：ET和CGRP的变化与脑血管损伤程度关系密切，有助于判断病情和评价疗效。
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| 关 键 词： | 急性脑梗死 内皮素 降钙素基因相关肽 |
| 收稿时间： | 2006-03-13 |
| 修稿时间： | 2006-03-13 |
Clinical Significance of Determination of Plasma ET and CGRP Levels in Patients with Acute Cerebral Infarction |
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| Xi Baoshan,Lin Lan,Wu Yubin. Clinical Significance of Determination of Plasma ET and CGRP Levels in Patients with Acute Cerebral Infarction[J]. Journal of Radioimmanology, 2006, 19(3): 173-175 |
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| Authors: | Xi Baoshan Lin Lan Wu Yubin |
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| Abstract: | Objective To investigate the clinical significance of changes of plasma endothelin(ET) and calcitonin-gene-related peptide(CGRP) in patients with acute cerebral infarction.Methods Plasma levels of endothelin and calcitonin-gene-related peptide(CGRP) were determined with RIA in 42 patients with acute cerebral infarction both before and after 28 days' treatment as well as in 38 controls.Results Before treatment,the plasma ET levels in the patients were significantly higher than those in controls,while the CGRP levels were significantly lower.ET levels decrcased significantly and CGRP levels increased significantly after treatment(P<0.01).Conclusion Determination of plasma ET and CGRP levels was helpful for the perdiction of treatment efficacy. |
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| Keywords: | infarction endothelin calcitonin - gene - related peptide |
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