| 慢性丙型肝炎患者血清leptin含量与HA、PⅢP水平的相关分析 |
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| 引用本文： | 宋皆金,周国平.慢性丙型肝炎患者血清leptin含量与HA、PⅢP水平的相关分析[J].放射免疫学杂志,2008,21(3):217-219. |
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| 作者姓名： | 宋皆金 周国平 |
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| 作者单位： | 1. 常州市钟楼医院检验科,213003
2. 常州市第三人民医院检验科,213003 |
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| 摘 要： | 目的：探讨了慢性丙型肝炎患者血清leptin含量与HA、PⅢP水平的关系。方法：应用放射免疫分析对32例慢性丙型肝炎患者进行了血清leptin和HA、PⅢP水平检测，并与35名正常健康人作比较。结果：慢性丙型肝炎患者血清leptin和HA、PⅢP水平均非常显著地高于正常人组（P〈0．01），相关分析显示，血清leptin与HA、PⅢP水平呈明显的正相关（r=0．6178．0．5706，P〈0．01）。结论：慢性丙型肝炎患者血清leptin水平的升高与肝脏炎症病变严重程度有关，leptin测定可作为—个判断肝脏炎症严重程度的指标，具有重要的临床价值。
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| 关 键 词： | 慢性丙型肝炎 瘦素 透明质酸 Ⅲ型前胶原肽 |
Study on the Relationship Between Serum Leptin and HA, PⅢP Levels in Patients with Chronic Hepatitis C |
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| Song Jiejin,Zhou Guoping.Study on the Relationship Between Serum Leptin and HA, PⅢP Levels in Patients with Chronic Hepatitis C[J].Journal of Radioimmanology,2008,21(3):217-219. |
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| Authors: | Song Jiejin Zhou Guoping |
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| Institution: | Song Jiejin , Zhou Guoping( 1 Department of Laboratory Medicine, Changzhou Zhonglou ttospital,Jiangsu (213003); 2Department of Laboratory Medicine, Changzhou No. 3 People＇s Hospital, Jiangsu (213003) ) |
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| Abstract: | Objective To explore the relationship between serum leptin and HA, PⅢP levels in patients with chronic hepatitis C. Methods Serum leptin, HA and PⅢP levels were measured with RIA in 32 patients with chronic hepatitis C and 35 controls. Resuits Serum leptin, HA and PⅢP levels were significantly higher in patients with chronic hepatitis C than those in controls （P 〈 0.01）, Serum levels of leptin were positively correlated with HA, PⅢP levels （r=0. 6178, 0. 5706, P〈0.01）. Conclusion Serurn leptin can be regarded as an indicator which reflects the severity of liver in flammation, and is of important clinical values. |
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| Keywords: | chronic hepatitis C leptin hyaluronie acid （HA） proeollagen type Ⅲ （PⅢP） |
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