骨质疏松性椎体压缩骨折的生物力学研究进展

骨质疏松有关的椎体压缩骨折经常发生在胸腰段的移行区域,是老年患者最早由骨质疏松恶化的骨折迹象,这种骨折可以看作是椎体负荷应力超过本身结构强度时发生的力学事件。对于骨质疏松患者,防止骨质疏松性骨折的发生是所有预防措施、治疗以及研究骨质疏松症的主要目标。通过综述近年来在生物力学方面研究骨质疏松性椎体压缩骨折的新进展,倡导骨质疏松患者及早预防椎体压缩骨折的发生,并在日常生活中避免一些超出椎体负荷安全范围的活动,预防椎体骨折级联的发生。

Biomechanical research progress of osteoporotic vertebra compressive fracture

Osteoporosis (OP)-related vertebral fractures often occur in the transitional thoracolumbar region, which are the earliest signs of OP deterioration in elderly patients. Such fractures can be regarded as a physical incident that occurs when the vertebral stress load exceeds the mechanical structural strength. To OP patients, preventing the occurrence of OP fracture is the primary goal for preventative measures, treatment and research of OP. This paper reviews the biomechanical research progress of osteoporotic vertebra compressive fracture (OVCF), and advocates early prevention of OVCF in OP patients, who should avoid activities that might exceed the security scope of the vertebral body load in daily life, so as to prevent subsequent fractures of the vertebral fracture cascade.