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基于虚拟仪器技术的血管生物反应器系统的研制
引用本文:陈明东,张正西,郭新,孙庆兰.基于虚拟仪器技术的血管生物反应器系统的研制[J].医用生物力学,2009,24(1):34-38.
作者姓名:陈明东  张正西  郭新  孙庆兰
作者单位:军事医学院 卫生装备研究所;南方医科大学 生物医学工程学院;军事医学院 卫生装备研究所;军事医学院 卫生装备研究所;军事医学院 卫生装备研究所
基金项目:国家重点基础研究发展计划(973计划)(2005CB623904);天津市自然科学基金重点项目(06YFJZJC02000)
摘    要:目的 生物反应器是组织工程研究的重要载体。本文构造了一种基于虚拟仪器技术的血管生物反应器系统研究平台。方法 系统使用曲柄滑块机构压缩和拉伸波纹管,模拟出人体血管内的搏动流。同时利用LabVIEW平台对压力等参数进行测量和控制,系统与PC机连接,可实现远程监控,使整个组织工程生物反应器系统初步实现分步式,自动化。结果 实验结果表明,该生物反应器能够对细胞施加合适的生物力学刺激,并准确检测各项参数。结论 基于虚拟仪器技术构造的血管生物反应器系统研究平台具有较大的应用推广价值。

关 键 词:生物反应器  虚拟仪器  LabVIEW  组织工程  生物力学  
收稿时间:1/6/2009 12:00:00 AM
修稿时间:1/6/2009 12:00:00 AM

Development of Bioreactor System for the Blood Vessel Based on Virtual Instrument
CHEN Ming-dong,ZHANG Zhen-xi,GUO Xin and SUN Qin-lan.Development of Bioreactor System for the Blood Vessel Based on Virtual Instrument[J].Journal of Medical Biomechanics,2009,24(1):34-38.
Authors:CHEN Ming-dong  ZHANG Zhen-xi  GUO Xin and SUN Qin-lan
Institution:The Institute of Medical Equipment, Academy of Military Medical Science; The School of Biomedical Engineering, South Medical University;The Institute of Medical Equipment, Academy of Military Medical Science;The Institute of Medical Equipment, Academy of Military Medical Science;The Institute of Medical Equipment, Academy of Military Medical Science
Abstract:Objective The bioreactor is an important facility for tissue engineering research. A research platform of bioreactor system for blood vessel on the virtual instrument was built. Method Slider-crank mechanism was used in this system to strain the bellows so as to simulate pulse flow of human blood vessels. This system can measure and control such parameters as pressure by using LabVIEW platform, and by connected with PC, the remote watch and control could be realized, which primarily achieved step-control and automatization. Result Experiments show that the bioreactor was able to exert appropriate biomechanical stimulation to cells, and detect various parameters accurately. Conclusions This bioreactor system for bloodvessel on the virtual instrument was valuable in practical application.
Keywords:Bioreactor  Virtual instrument  LabVIEW  Tissue engineering  Biomechanics
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